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Der Onkologe

, Volume 15, Issue 4, pp 352–358 | Cite as

Pathologie der Weichgewebssarkome

  • D. Katenkamp
  • K. KatenkampEmail author
Leitthema
  • 173 Downloads

Zusammenfassung

Den Ausführungen der Arbeit wird die aktuelle Klassifikation der Weichgewebstumoren durch die WHO (2002) zugrunde gelegt. Neben voll malignen Tumoren gibt es jetzt Neubildungen von intermediärer Malignität. Merkmale solcher Geschwülste sind entweder ein lokal aggressives Wachstum ohne Metastasen oder nur sehr selten im Krankheitsverlauf auftretende Metastasen (in weniger als 2% der Fälle). Unter Berücksichtigung dieser Untergliederung werden die Tumoren mit adipozytischer, fibroblastischer/myofibroblastischer, sog. fibrohistiozytischer, muskulärer, vaskulärer und ungewisser Differenzierung kurz charakterisiert. Die Tumoren mit Nervenscheidendifferenzierung werden aktuell nicht mehr unter den Weichgewebstumoren geführt. Es folgen des Weiteren einige Bemerkungen zur Sicherheit der morphologischen Diagnose bei sehr kleinen bioptischen Gewebeproben und zur Graduierung der Malignität.

Schlüsselwörter

Dignität der Weichgewebstumoren Klassifikation von malignen Weichgewebstumoren Pathologie der Weichgewebssarkome Diagnosesicherheit Malignitätsgraduierung 

Pathology of soft tissue sarcomas

Abstract

This article is based on the latest (2002) classification of soft tissue tumors by the World Health Organization (WHO). The WHO currently distinguishes between soft tissue tumors with full malignancy and neoplasms with intermediate malignancy. The latter tumors are divided into locally aggressive forms without metastatic potential and neoplasms with rare metastases (in less than 2% of cases). Considering this classification, tumors of adipocytic, fibroblastic/myofibroblastic, so-called fibrohistiocytic, muscular, vascular, and uncertain differentiation are characterized. Tumors with nerve sheath differentiation have been eliminated from the category of soft tissue tumors. This article also includes some remarks concerning malignancy grading and the certainty of the morphological diagnosis if only very small biopsies are available.

Keywords

Dignity of soft tissue tumors Classification of malignant soft tissue tumors Pathology of soft tissue sarcomas Certainty of diagnosis Grading of malignancy 

Notes

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

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Copyright information

© Springer Medizin Verlag 2009

Authors and Affiliations

  1. 1.Institut für PathologieFriedrich-Schiller-Universität JenaJenaDeutschland

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