Der Onkologe

, Volume 12, Issue 4, pp 337–344

25 Jahre Deutsche Hodgkin Studiengruppe

Ein Beitrag zur Versorgungsforschung?
Leitthema
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Zusammenfassung

Mittels prospektiv-randomisierter klinischer Studien der Deutschen Hodgkin Studiengruppe (DHSG) konnten in den letzten 40 Jahren systematisch Verbesserungen im Bereich von Strahlen- und Polychemotherapie umgesetzt werden. So entwickelte sich das Hodgkin-Lymphom von einer unheilbaren malignen Erkrankung zu derjenigen Malignität mit der besten Prognose in der Erwachsenenonkologie. Neben den Verbesserungen der Therapieergebnisse konnten auch diagnostische Standards weiter entwickelt werden. Wesentliches Strukturmerkmal der DHSG ist die multidisziplinäre Zusammenarbeit von internistischer Onkologie, Strahlentherapie, diagnostischer Radiologie, Nuklearmedizin und Biostatistik. In 5 aufeinander folgenden Studiengenerationen zur Primärtherapie des Hodgkin-Lymphoms konnte durch intensive Kooperation verschiedener Fachbereiche auch ein Beitrag zur Qualitätssicherung geleistet werden.

Schlüsselwörter

Hodgkin-Lymphom Klinische Studien Primärtherapie Qualitätssicherung 

25 years German Hodgkin Study Group

Acontribution to health care research?

Abstract

Over the past 40 years, treatment of Hodgkin’s lymphoma has changed from an almost fatal prognosis to a prototype illness for curative treatment strategies in adult oncology. A substantial impact on this development was contributed by the prospective-randomized clinical trials organised by the German Hodgkin Study Group. In addition to improvements in therapy outcome, the trial work provided benefits in diagnostics and quality assurance. Close collaboration between medical oncology, radiotherapy, radiology, nuclear medicine, and biostatistics is characteristic of the GHSG.

Keywords

Hodgkin’s lymphoma Clinical trials Primary therapy Quality assurance 

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Copyright information

© Springer Medizin Verlag 2006

Authors and Affiliations

  1. 1.Klinik für Innere Medizin, Universitätsklinikum Köln
  2. 2.Klinik für Innere Medizin, Universitätsklinikum KölnKöln

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