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Archives of Women's Mental Health

, Volume 22, Issue 1, pp 85–91 | Cite as

Impact of maternal depression on perinatal outcomes in hospitalized women—a prospective study

  • Narkis HermonEmail author
  • Tamar Wainstock
  • Eyal Sheiner
  • Agneta Golan
  • Asnat Walfisch
Original Article
  • 185 Downloads

Abstract

Scarce data exists regarding the prevalence of antenatal depression in hospitalized pregnant women, and its effect on perinatal outcome. We aimed to estimate the risk of maternal depression among women hospitalized in a high-risk pregnancy department, and to evaluate its potential association with adverse perinatal outcome. A depression screening self-questionnaire-based prospective study was performed, in which hospitalized pregnant women who screened positive for depression were compared to those who screened negative. The Edinburgh Postnatal Depression Scale (EPDS) was used for antenatal depression screening. Pregnancy course and perinatal outcome were compared between the groups. A multivariate logistic regression model was constructed to control for clinically relevant confounders. During the study period, 279 women met the inclusion criteria. Among them, 28.3% (n = 79) screened positive for depression (≥ 10 points on the EPDS). In the univariate analysis, a significantly higher incidence of preterm delivery (< 37 weeks), low birthweight (< 2500 g), low Apgar scores (at 1 and 5 min), and neonatal intensive care unit (NICU) admissions were noted among the screen positive group. In the multivariate regression model, controlled for maternal age, ethnicity, gestational diabetes mellitus, preeclampsia, past preterm delivery, and gestational age upon admission, maternal antenatal depression during hospitalization was noted as an independent risk factor for preterm delivery (adjusted OR 3.32, 95%CI 1.16–9.52, p = 0.026). Maternal antenatal depression during hospitalization is very common and appears to play a significant and independent role in the prediction of preterm delivery.

Keywords

Antenatal depression High-risk pregnancy Screening EPDS 

Notes

Compliance with ethical standards

The study was approved by the local institutional ethical review board (SUMC IRB).

Conflict of interest

The authors report no conflict of interest. This study was conducted as part of the requirements for graduation from the Medical School of the Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel.

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Narkis Hermon
    • 1
    Email author
  • Tamar Wainstock
    • 2
  • Eyal Sheiner
    • 3
  • Agneta Golan
    • 4
  • Asnat Walfisch
    • 3
  1. 1.Joyce and Irving Goldman Medical School, Faculty of Health SciencesBen-Gurion University of the NegevBeer-ShevaIsrael
  2. 2.The Department of Public Health, Faculty of Health SciencesBen-Gurion University of the NegevBeer-ShevaIsrael
  3. 3.Department of Obstetrics and GynecologySoroka University Medical Center, Ben-Gurion University of the NegevBeer-ShevaIsrael
  4. 4.Neonatal Intensive Care UnitSoroka University Medical Center, Ben-Gurion University of the NegevBeer-ShevaIsrael

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