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Archives of Women's Mental Health

, Volume 10, Issue 3, pp 125–127 | Cite as

Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): a case series

  • L. N. Ravindran
  • S.-A. Woods
  • M. Steiner
  • A. V. Ravindran
Short communication

Summary

The efficacy and tolerability of symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD) was evaluated in an open trial. Eight outpatients, aged 18–45 years and diagnosed with PMDD, were treated with 10–20 mg of citalopram from the start of premenstrual symptoms until the onset of menses. Primary efficacy variables were the premenstrual tension scale (PMTS-O) and the clinical global impression of improvement (CGI). Treatment was associated with significant improvement in PMDD symptoms (p < 0.001).

Keywords: Citalopram; premenstrual dysphoric disorder; psychopharmacology; symptom-onset dosing. 

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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • L. N. Ravindran
    • 1
  • S.-A. Woods
    • 2
  • M. Steiner
    • 3
  • A. V. Ravindran
    • 1
  1. 1.Department of PsychiatryUniversity of TorontoTorontoCanada
  2. 2.Department of PsychiatryUniversity of OttawaOttawaCanada
  3. 3.Department of PsychiatryMcMaster UniversityHamiltonCanada

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