SECRETOOL: integrated secretome analysis tool for fungi
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The secretome (full set of secreted proteins) has been studied in multiple fungal genomes to elucidate the potential role of those protein collections involved in a number of metabolic processes from host infection to wood degradation. Being aminoacid composition a key factor to recognize secretory proteins, SECRETOOL comprises a group of web tools that enable secretome predictions out of aminoacid sequence files, up to complete fungal proteomes, in one step. SECRETOOL is freely available on the web at http://genomics.cicbiogune.es/SECRETOOL/Secretool.php.
KeywordsProtein secretion Signal peptide Secretome Bioinformatics Analysis pipeline
We thank J. Ferrero for his advice with Perl/CGI scripting. ARC, AMA, JLL and the research expenses are supported by the Gov. of the Basque Country (Etortek Research Programs 2011/2013) and from the Innovation Technology Dept. of Bizkaia. MA and JAO are supported by research projects AGL2011-30495 of the Spanish National Research Plan, Bioethanol-Euroinnova from the Autonomous Gov. of Navarre and by additional support from the Public University of Navarre.
Conflict of interest
The authors declare that they have no conflict of interest.
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