Amino Acids

, Volume 46, Issue 2, pp 471–473 | Cite as

SECRETOOL: integrated secretome analysis tool for fungi

  • Ana R. Cortázar
  • Ana M. Aransay
  • Manuel Alfaro
  • José A. Oguiza
  • José L. Lavín
Short Communication


The secretome (full set of secreted proteins) has been studied in multiple fungal genomes to elucidate the potential role of those protein collections involved in a number of metabolic processes from host infection to wood degradation. Being aminoacid composition a key factor to recognize secretory proteins, SECRETOOL comprises a group of web tools that enable secretome predictions out of aminoacid sequence files, up to complete fungal proteomes, in one step. SECRETOOL is freely available on the web at


Protein secretion Signal peptide Secretome Bioinformatics Analysis pipeline 



We thank J. Ferrero for his advice with Perl/CGI scripting. ARC, AMA, JLL and the research expenses are supported by the Gov. of the Basque Country (Etortek Research Programs 2011/2013) and from the Innovation Technology Dept. of Bizkaia. MA and JAO are supported by research projects AGL2011-30495 of the Spanish National Research Plan, Bioethanol-Euroinnova from the Autonomous Gov. of Navarre and by additional support from the Public University of Navarre.

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

726_2013_1649_MOESM1_ESM.pdf (56 kb)
Supplementary material 1 (PDF 56 kb)


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Copyright information

© Springer-Verlag Wien 2013

Authors and Affiliations

  • Ana R. Cortázar
    • 1
  • Ana M. Aransay
    • 1
  • Manuel Alfaro
    • 2
  • José A. Oguiza
    • 2
  • José L. Lavín
    • 1
  1. 1.Genome Analysis PlatformCIC bioGUNE and CIBERehdDerioSpain
  2. 2.Department of Agrarian Production, Genetics and Microbiology Research GroupPublic University of NavarrePamplonaSpain

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