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Amino Acids

, Volume 35, Issue 1, pp 243–245 | Cite as

Neutrophil fatty acid composition: effect of a single session of exercise and glutamine supplementation

  • C. J. Lagranha
  • T. C. Alba-Loureiro
  • E. F. Martins
  • T. C. Pithon-Curi
  • R. Curi
Short Communication

Summary.

The fatty acid composition of immune cells appears to contribute to variations of cell function. The independent and combined effects of a single session of exercise (SSE) and glutamine supplementation (GS) on neutrophil fatty acid composition were investigated. Compared to control (no treatment given – i.e. neither SSE or GS), single session of exercise decreased myristic, palmitic and eicosapentaenoic (EPA) acids, and increased lauric, oleic, linoleic, arachidonic (AA) and docosahexaenoic (DHA) acids whereas glutamine supplementation combined with SSE (GS+SSE) increased oleic acid. Polyunsaturated/saturated fatty acid ratio and Unsaturation index were higher in neutrophils from the SSE and GS groups as compared with control. These findings support the proposition that SSE and GS may modulate neutrophil function through alterations in fatty acid composition.

Keywords: Fatty acid composition – Neutrophils – Glutamine supplementation – Single session of exercise 

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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • C. J. Lagranha
    • 1
  • T. C. Alba-Loureiro
    • 1
  • E. F. Martins
    • 1
  • T. C. Pithon-Curi
    • 2
  • R. Curi
    • 1
  1. 1.Department of Physiology and Biophysics, Institute of Biomedical SciencesUniversity of São PauloSão PauloBrazil
  2. 2.Institute of Biomedical and Health SciencesCruzeiro do Sul UniversitySão PauloBrazil

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