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Amino Acids

, Volume 28, Issue 4, pp 373–376 | Cite as

Using pseudo amino acid composition to predict protein subcellular location: Approached with Lyapunov index, Bessel function, and Chebyshev filter

  • Y. Gao
  • S. Shao
  • X. Xiao
  • Y. Ding
  • Y. Huang
  • Z. Huang
  • K.-C. Chou
Article

Summary.

With the avalanche of new protein sequences we are facing in the post-genomic era, it is vitally important to develop an automated method for fast and accurately determining the subcellular location of uncharacterized proteins. In this article, based on the concept of pseudo amino acid composition (Chou, K.C. Proteins: Structure, Function, and Genetics, 2001, 43: 246–255), three pseudo amino acid components are introduced via Lyapunov index, Bessel function, Chebyshev filter that can be more efficiently used to deal with the chaos and complexity in protein sequences, leading to a higher success rate in predicting protein subcellular location.

Keywords: Covariant-discriminant algorithm – Pseudo amino acid composition – Chaos – Lyapunov index – Bessel function – Chebyshev filter 

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Copyright information

© Springer-Verlag/Wien 2005

Authors and Affiliations

  • Y. Gao
    • 1
  • S. Shao
    • 1
  • X. Xiao
    • 1
    • 2
  • Y. Ding
    • 1
  • Y. Huang
    • 1
  • Z. Huang
    • 1
  • K.-C. Chou
    • 1
    • 3
    • 4
    • 5
  1. 1.Bioinformation Research Centre, Donghua UniversityShanghaiChina
  2. 2.Jing-De-Zhen Ceramic InstituteJing-De-ZhenChina
  3. 3.Shanghai Jiaotong UniversityShanghaiChina
  4. 4.Tianjin Institute of Bioinformatics & Drug DiscoveryTianjinChina
  5. 5.Gordon Life Science Institute, Torrey Del MarSan DiegoU.S.A.

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