Determination of Enantiomeric Excess of Leucine by 13C CP-MAS Solid-State NMR
Article
Received:
Abstract.
The enantiomeric excess can be determined by many methods. One of them is nuclear magnetic resonance in solid state (SS-NMR). In this study we used the SS-NMR experiment of one-dimensional exchange spectroscopy by sideband alteration for determination of the enantiomeric excess of leucine. The density functional theory gauge-including atomic orbital calculations were used to assign all signals in 13C cross polarization magic-angle spinning spectra for two different molecules in the crystal lattice of L-leucine.
Keywords
Nuclear Magnetic Resonance Leucine Racemate Nuclear Magnetic Resonance Spectroscopy Enantiomeric Excess
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
- Fyfe, C.A.: Solid State NMR for Chemists. CFC Press, Guelph, Ontario (1983)Google Scholar
- Mehring, M.: Principles of High Resolution NMR in Solids. Springer, Berlin (1983)Google Scholar
- Yannoni, C.S.: Acc. Chem. Res. 15, 201 (1982)CrossRefGoogle Scholar
- Schaefer, J., Stejskal, E.O.: J. Am. Chem. Soc. 98, 1031 (1976)CrossRefGoogle Scholar
- Hill, H.D., Zens, A.P., Jacobus, J.: J. Am. Chem. Soc. 101, 7090–7091 (1979)CrossRefGoogle Scholar
- Bragg, W.L.: The Crystalline State. Bell and Sons, London (1955)Google Scholar
- Stout, G.H., Jensen, L.H.: X-Ray Structure Determination, p. 144. Macmillan, New York (1968)Google Scholar
- Andersen, K.V., Bilsøre, H., Jacobsen, J.: Magn. Reson. Chem. 28, S47–S51 (1990)CrossRefGoogle Scholar
- Frey, M.H., Opella, S.J.: J. Chem. Soc. Chem. Commun. 1980, 474 (1980)CrossRefGoogle Scholar
- Hollingsworth, M.D., Cyr, N.: J. Chem. Soc. Chem. Commun. 1990, 578 (1990)CrossRefGoogle Scholar
- Belton, P.S., Gil, A.M., Tanner, S.F.: Solid State Nucl. Magn. Reson. 1, 67–71 (1992)CrossRefGoogle Scholar
- Wei, Y., Lee, D.-K., McDermott, A.E., Ramamoorthy, A.: J. Magn. Reson. 158, 23 (2002)CrossRefADSGoogle Scholar
- Frisch, M.J., Trucks, G.W., Schlegel, H.B., Scuseria, G.E., Robb, M.A., Cheeseman, J.R., Montgomery, J.A. Jr., Vreven, T., Kudin, K.N., Burant, J.C., Millam, J.M., Iyengar, S.S., Tomasi, J., Barone, V., Mennucci, B., Cossi, M., Scalmani, G., Rega, N., Petersson, G.A., Nakatsuji, M., Hada, M., Ehara, K., Toyota, R., Fukuda, J., Hasegawa, M., Ishida, T., Nakajima, Y., Honda, H., Kitao, O., Nakai, H., Klene, M., Li, X., Knox, J.E., Hratchian, H.P., Cross, J.B., Adamo, C., Jaramillo, J., Gomperts, R., Stratmann, R.E., Yazyev, O., Austin, A.J., Cammi, R., Pomelli, C., Ochterski, J.W., Ayala, P.Y., Morokuma, K., Voth, G.A., Salvador, P., Dannenberg, J.J., Zakrzewski, V.G., Dapprich, S., Daniels, A.D., Strain, M.C., Farkas, O., Malick, D.K., Rabuck, A.D., Raghavachari, K., Foresman, J.B., Ortiz, J.V., Cui, Q., Baboul, A.G., Clifford, S., Cioslowski, J., Stefanov, B.B., Liu, G., Liashenko, A., Piskorz, P., Komaromi, I., Martin, R.L., Fox, D.J., Keith, T., Al-Laham, M.A., Peng, C.Y., Nanayakkara, A., Challacombe, M., Gill, P.M.W., Johnson, B., Chen, W., Wong, M.W., Gonzalez, C., Pople, J.A.: Gaussian 03, Revision C.02. Gaussian Inc., Wallingford, Conn. (2004)Google Scholar
- Schaftenaar, G., Noordik, J.H.: J. Comput. Aided Mol. Des. 14, 123–134 (2000)CrossRefGoogle Scholar
- Gorbitz, C.H., Dalhus, B.: Acta Crystallogr. Sect. C: Cryst. Struct. Commun. 52, 1754 (1996)CrossRefGoogle Scholar
- Blasio, B., Pedone, C., Sirigu, A.: Acta Crystallogr. Sect. B: Struct. Crystallogr. Cryst. Chem. 31, 601 (1975)CrossRefGoogle Scholar
- Liu, F., Phung, D.W., Alderman, D.W., Grant, D.M.: J. Am. Chem. Soc. 118, 10629 (1996)CrossRefGoogle Scholar
Copyright information
© Springer-Verlag 2008