Stomatologie

, Volume 109, Issue 4–5, pp 35–39 | Cite as

Die orale Bürstenabstrichmethode zur Bestimmung von humanen Papillomavirus (HPV)-Infektionen

  • D. Dalla Torre
  • E. Sölder
  • D. Burtscher
  • A. Widschwendter
  • C. Steger
  • W. Puelacher
Originalarbeit

Zusammenfassung

Humane Papillomaviren (HPVs) gelten als kausale Ursache bei der Entstehung maligner Tumore. Die vorliegende Untersuchung bewertet die Anwendung der in der Gynäkologie als Routineverfahren verwendeten HPV-Abstrichmethode (Digene Cervical Sampler®) im Rahmen der oralen HPV-Diagnostik. Es wird die Methodik des Verfahrens beschrieben, Reliabilitätsbestimmungen und Fehlermöglichkeiten bewertet und die Studienergebnisse mit Ergebnissen der aktuellen Literatur verglichen. Die Digene Cervical Sampler HC2 Hybrid Capture®-Diagnostik (Digene Cervical Sampler® in Kombination mit Hybrid Capture II® Assay) stellt ein zuverlässiges und kostengünstiges Verfahren in der oralen high-risk- und low-risk-HPV-Diagnostik dar.

Schlüsselwörter

Humanes Papillomavirus (HPV) HPV-Screening Bürstenabstrich Maligne Tumore Plattenepithelkarzinom 

Brush Smear approach for detection of human papilloma virus in oral mucosa

Summary

The human papilloma viruses (HPVs) are known to be causal factors in the development malign tumors. The study investigates a smear test, routinely used in gynecology for HPV-diagnosis in cervical lesions, for oral HPV-detection. The procedure is evaluated and the reliability and potential failures are evaluated. The Digene Cervical Sampler HC2 Hybrid Capture® procedure represents a reliable and low-price method in the diagnosis of high and low risk oral HPV-infection.

Keywords

Human Papillomavirus (HPV) HPV-Screening Oral brush smear Malign tumors Squamous cell carcinoma 

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • D. Dalla Torre
    • 1
  • E. Sölder
    • 2
  • D. Burtscher
    • 3
  • A. Widschwendter
    • 2
  • C. Steger
    • 4
  • W. Puelacher
    • 1
  1. 1.Univ. Klinik für Mund-, Kiefer- und Gesichtschirurgie, Laboratorium für GewebetechnologieMedizinische Universität InnsbruckAustria
  2. 2.Univ. Klinik für Gynäkologie und GeburtshilfeMedizinische Universität InnsbruckAustria
  3. 3.Univ. Klinik für Zahnerhaltung und ZahnersatzMedizinische Universität InnsbruckAustria
  4. 4.Department für PathologieMedizinische Universität InnsbruckAustria

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