Abscisic-acid-dependent basic leucine zipper (bZIP) transcription factors in plant abiotic stress
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One of the major causes of significant crop loss throughout the world is the myriad of environmental stresses including drought, salinity, cold, heavy metal toxicity, and ultraviolet-B (UV-B) rays. Plants as sessile organisms have evolved various effective mechanism which enable them to withstand this plethora of stresses. Most of such regulatory mechanisms usually follow the abscisic-acid (ABA)-dependent pathway. In this review, we have primarily focussed on the basic leucine zipper (bZIP) transcription factors (TFs) activated by the ABA-mediated signalosome. Upon perception of ABA by specialized receptors, the signal is transduced via various groups of Ser/Thr kinases, which phosphorylate the bZIP TFs. Following such post-translational modification of TFs, they are activated so that they bind to specific cis-acting sequences called abscisic-acid-responsive elements (ABREs) or GC-rich coupling elements (CE), thereby influencing the expression of their target downstream genes. Several in silico techniques have been adopted so far to predict the structural features, recognize the regulatory modification sites, undergo phylogenetic analyses, and facilitate genome-wide survey of TF under multiple stresses. Current investigations on the epigenetic regulation that controls greater accessibility of the inducible regions of DNA of the target gene to the bZIP TFs exclusively under stress situations, along with the evolved stress memory responses via genomic imprinting mechanism, have been highlighted. The potentiality of overexpression of bZIP TFs, either in a homologous or in a heterologous background, in generating transgenic plants tolerant to various abiotic stressors have also been addressed by various groups. The present review will provide a coherent documentation on the functional characterization and regulation of bZIP TFs under multiple environmental stresses, with the major goal of generating multiple-stress-tolerant plant cultivars in near future.
KeywordsAbscisic-acid Epigenetics In silico analyses Basic leucine zipper Transcription factors Transgenic plants
Financial support from Science and Engineering Research Board (SERB), Government of India through the research grant (SR/FT/LS-65/2010) and from Council of Scientific and Industrial Research (CSIR), Government of India through the major grant [38(1387)/14/EMR-II] to Dr. Aryadeep Roychoudhury is gratefully acknowledged.
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Conflict of interest
The authors declare that they have no conflict of interest for publication of this manuscript.
- Avashthi H, Gautam B, Jain PA, Tiwari A, Pathak RK, Srivastava A, Taj G, Kumar A (2014) In silico identification of MAPK3/6 substrates in WRKY, bZIP, MYB, MYB- related, NAC and AP-2 transcription factor family in Arabidopsis thaliana. Int J Comput Bioinfo In Silico Model 3:454–459Google Scholar
- Banerjee A, Roychoudhury A (2015a) Group II late embryogenesis abundant (LEA) proteins: structural and functional aspects in plant abiotic stress. Plant Growth Regul DOI: 10.1007/s10725-015-0113-3
- Basu S, Roychoudhury A (2014) Computational analysis of abiotic stress inducible genes and proteins from rice (Oryza sativa L.). Int J Pharm Bio Sci 5(B):718–735Google Scholar
- Gonzalez-Guzman M, Pizzio GA, Antoni R, Vera-Sirera F, Merilo E, Bassel GW et al (2012) Arabidopsis PYR/PYL/RCAR receptors play a major role in quantitative regulation of stomatal aperture and transcriptional response to abscisic acid. Plant Cell 24:2483–2496CrossRefPubMedPubMedCentralGoogle Scholar
- Hayami N, Sakai Y, Kimura M, Tokizawa M, Iuchi S et al. (2015) The responses of Arabidopsis ELIP2 1 to UV-B, high light, and cold stress are regulated by a transcriptional regulatory unit composed of two elements. Plant Physiol DOI: 10.1104/pp.15.00398
- Huang X-S, Liu J-H, Chen Huang X-J et al (2010) Overexpression of PtrABF gene, a bZIP transcription factor isolated from Poncirus trifoliata, enhances dehydration and drought tolerance in tobacco via scavenging ROS and modulating expression of stress-responsive genes. BMC Plant Biol 10:230CrossRefPubMedPubMedCentralGoogle Scholar
- Kobayashi Y, Murata M, Minami H, Yamamoto S, Kagaya Y, Hobo T, Yamamoto A, Hattori T (2005) Abscisic acid-activated SNRK2 protein kinases function in the gene-regulation pathway of ABA signal transduction by phosphorylating ABA response element-binding factors. Plant J 44:939–949CrossRefPubMedGoogle Scholar
- Liu N, Ding Y, Fromm M, Avramova Z (2014) Different gene-specific mechanisms determine the ‘revised-response’ memory transcription patterns of a subset of A. thaliana dehydration stress responding genes. Nucleic Acids Res 2014:1–11Google Scholar
- Ma Y, Szostkiewicz I, Korte A, Moes D, Yang Y, Christmann A et al (2009) Regulators of PP2C phosphatase activity function as abscisic acid sensors. Sci 324:1064–1068Google Scholar
- Nicolas P, Lecourieux D, Kappel C, Cluzet S, Cramer G, Delrot S, Lecourieux F (2014) The basic leucine zipper transcription factor ABSCISIC ACID RESPONSE ELEMENT-BINDING FACTOR2 is an important transcriptional regulator of abscisic acid-dependent grape berry ripening processes. Plant Physiol 164:365–383CrossRefPubMedGoogle Scholar
- Roychoudhury A, Gupta B, Sengupta DN (2008) Trans-acting factor designated OSBZ8 interacts with both typical abscisic acid responsive elements as well as abscisic acid responsive element like sequences in the vegetative tissues of indica rice cultivars. Plant Cell Rep 27:779–794CrossRefPubMedGoogle Scholar
- Roychoudhury A, Paul A (2012) Abscisic acid-inducible genes during salinity and drought stress. In: Berhardt LV (ed) Advances in Medicine and Biology, vol 51. Nova Publishers, New York, pp 1–78Google Scholar
- Sanchita BBM, Sharma A (2013) In silico analysis of putative transcription factor binding sites in differentially expressed genes: study of the turnover of TFBSs under salt stress responsiveness in solanaceae family. Plant Omics J 6:278–285Google Scholar
- Soares-Cavalcanti NM, Belarmino LC, Kido EA, Wanderley-Nogueira AC, Bezerra-Neto JP, Cavalcanti-Lira R, Pandolfi V, Nepomuceno AL et al (2012) In silico identification of known osmotic stress responsive genes from Arabidopsis in soybean and Medicago. Genet Mol Biol 35(suppl 1):315–321CrossRefPubMedPubMedCentralGoogle Scholar
- Yoshida T, Fujita Y, Maruyama K, Mogami J, Todaka D, Shinozaki K, Yamaguchi-Shinozaki K (2015) Four Arabidopsis AREB/ABF transcription factors function predominantly in gene expression downstream of SnRK2 kinases in abscisic acid signalling in response to osmotic stress. Plant Cell Environ 38:35–49CrossRefPubMedGoogle Scholar
- Yoshida T, Fujita Y, Sayama H, Kidokoro S, Maruyama K et al (2010) AREB1, AREB2, and ABF3 are master transcription factors that cooperatively regulate ABRE-dependent ABA signaling involved in drought stress tolerance and require ABA for full activation. Plant J 61:672–685CrossRefPubMedGoogle Scholar