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Monatshefte für Chemie - Chemical Monthly

, Volume 150, Issue 11, pp 1993–1997 | Cite as

New synthesis of trimethylsilyl esters of phosphorus(III) acids

  • Vasily MorgalyukEmail author
  • Tatyana Strelkova
  • Valery Brel
Original Paper
  • 35 Downloads

Abstract

A novel synthetically important reaction has been developed for the quick, convenient, and high-yield preparation of trimethylsilyl esters of phosphorus(III) acids, synthetically valuable Michaelis–Arbuzov reaction precursors. Commercially and synthetically available initial compounds used are derivatives of propan-2-ol phosphorylated in the second position capable of long-term storage and available silylating reagents: hexamethyldisilazane, bis(trimethylsilyl)acetamide, and diethyl(trimethylsilyl)amine. Also, a stepwise reaction scheme of the starting compounds with silylating reagents has been proposed.

Graphic abstract

Keywords

Phosphorus(III) trimethylsilylether Phosphorus compounds Reaction mechanisms Retro reactions 

Notes

Acknowledgements

This work was performed with the financial support from the Ministry of Science and Higher Education of the Russian Federation using the Equipment of Center for Molecular Composition studies of INEOS RAS.

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Nesmeyanov Institute of Organoelement CompoundsRussian Academy of SciencesMoscowRussia

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