Monatshefte für Chemie - Chemical Monthly

, Volume 150, Issue 5, pp 957–959 | Cite as

100 years of mescaline

  • Mike Jay
Original Paper


In the hundred years since Ernst Späth’s synthesis of mescaline, it has been used in clinical research for many purposes, including the study of hallucinations, creativity, and schizophrenia. After Aldous Huxley described his experience with it in The Doors of Perception, it became a public sensation. During the 1960s it was largely replaced as a research compound by LSD. Today its scientific use is subject to strict controls, but the synthetic phenethylamines developed from it are widely used.

Graphical abstract


Mescaline Hallucinations Art Psychiatry LSD 



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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  • Mike Jay
    • 1
  1. 1.Centre for Health HumanitiesUniversity College LondonLondonUK

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