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An eco-benign and high speed protocol for the synthesis of 2-aroyl-3,5-diarylfuran derivatives using Teflon-supported iodine

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Abstract

A new, practical, and convenient approach has been established for the expeditious synthesis of bioactive 2-aroyl-3,5-diarylfurans in excellent yields using a iodine-impregnated Teflon by a microwave-promoted process. The products are isolated without tedious aqueous work-up in high purity. The microwave accelerated the reaction and renders the whole synthesis into a truly eco-friendly protocol.

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Acknowledgements

This work was supported by the Research Council at the University of Shahid Chamran.

Author information

Correspondence to Arash Mouradzadegun.

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Supplementary material 2 (MPG 1052 kb)

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Mouradzadegun, A., Ganjali, M.R., Abadast, F. et al. An eco-benign and high speed protocol for the synthesis of 2-aroyl-3,5-diarylfuran derivatives using Teflon-supported iodine. Monatsh Chem 149, 27–32 (2018) doi:10.1007/s00706-017-2061-2

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Keywords

  • 2-Aroyl-3,5-diarylfurans
  • Heterocycles
  • Iodine-impregnated Teflon
  • Green chemistry
  • Microwave-assisted synthesis