Monatshefte für Chemie - Chemical Monthly

, Volume 147, Issue 12, pp 2157–2161 | Cite as

l-Proline catalyzed condensation of salicylaldehydes with ethyl nitroacetate: an efficient access to 3-nitrocoumarins

Original Paper
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Accepted:

Abstract

l-Proline catalyzed condensation of salicylaldehydes and ethyl nitroacetate afforded 3-nitrocoumarins in good to high yields under mild conditions. This organocatalyzed process offers a much improved yield of 3-nitrocoumarins and well tolerates both electron-donating and electron-withdrawing substituents on the phenyl ring.

Graphical abstract

Keywords

Coumarins 3-Nitrocoumarins l-Proline Organocatalysis Salicylaldehyde 
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Notes

Acknowledgments

The authors thank BHU, Varanasi for financial support. Priyanka is thankful to CSIR, New Delhi, India for Senior Research Fellowship.

Supplementary material

706_2016_1736_MOESM1_ESM.docx (2.5 mb)
Supplementary material 1 (DOCX 2562 kb)

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Copyright information

© Springer-Verlag Wien 2016

Authors and Affiliations

  1. 1.Department of Chemistry, MMVBanaras Hindu UniversityVaranasiIndia

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