Monatshefte für Chemie - Chemical Monthly

, Volume 147, Issue 2, pp 405–412 | Cite as

Efficient and simple preparation of functionalized 1,1-dibromoenol phosphates

Original Paper

Abstract

The preparation of functionalized 1,1-dibromoalkenyl phosphates is described. The protocol developed for their preparation is based on the generation of enolates from α,α-dibromoketones followed by a reaction with dialkyl chlorophosphates. The procedure tolerates various functional groups including ester, ketone, and nitrile, and the yields are generally high.

Graphical abstract

Keywords

Bromination Alkynes Phosphates Enols 

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Copyright information

© Springer-Verlag Wien 2015

Authors and Affiliations

  • Vladislav Kotek
    • 1
  • Peter Polák
    • 1
  • Tomáš Tobrman
    • 1
  1. 1.Department of Organic ChemistryUniversity of Chemistry and TechnologyPrague 6Czech Republic

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