Molecular characterization of Italian bovine leukemia virus isolates reveals the presence of distinct phylogenetic clusters

  • Moira BazzucchiEmail author
  • Carmen Iscaro
  • Cristina Casciari
  • Monica Giammarioli
  • Francesco Feliziani
Brief Report


Disease caused by bovine leukemia virus (BLV) results in significant economic losses to the livestock industry. To date, there is only one report describing the strains found in Italy. BLV strains (n = 24), collected between 2012 and 2016 from four different Italian regions, were genetically analyzed by direct sequencing of a portion of the BLV env gene, and the sequences were compared with those in the GenBank database. The Italian BLVs clustered into genotypes G2, G4, G6, G7, and G8, revealing a high level of BLV genetic heterogeneity in Italy. This study provides a basis for further investigations into the evolutionary relationship between BLV strains.



We would like to thank Editage ( for English language editing.

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Conflict of interest

The authors declare no conflict of interest.

Supplementary material

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Supplementary material 1 (DOCX 24 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Istituto Zooprofilattico Sperimentale dell’Umbria e delle Marche Togo RosatiPerugiaItaly

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