Archives of Virology

, Volume 164, Issue 5, pp 1489–1492 | Cite as

Identification and complete genome characterization of human enterovirus 117 from a child with pneumonia in China

  • Juan Du
  • Teng Zhu
  • Lu Zhuang
  • Pan-He Zhang
  • Xiao-Ai Zhang
  • Qing-Bin LuEmail author
  • Wei LiuEmail author
Annotated Sequence Record


In this study, human enterovirus C117 (EV-C117) was detected in a 3-month-old boy diagnosed with pneumonia in China. A phylogenetic analysis showed that this strain was genetically closer to the Lithuanian strain than to the USA strain.



This study was supported by China Mega-Project for Infectious Diseases Grant (2017ZX10103004, 2018ZX10713002 and 2018ZX10101003), the Natural Science Foundation of China (81703274), and Peking University Medicine Seed Fund for Interdisciplinary Research (BMU2018MX009).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study protocol was reviewed and approved by the Ethics Review Committee of Children’s Hospital of Chongqing Medical University.

Informed consent

We obtained informed consent from the child’s parents.

Supplementary material

705_2019_4196_MOESM1_ESM.tif (1.3 mb)
Supplemental Figure 1 Phylogenetic trees constructed based on 5’UTR, VP4, VP2, VP3, 2A, 2B, 2C, 3A, 3B, 3C, 3D and 3’UTR sequences by the maximum-likelihood method in MEGA 7.0. The isolate from the present study is indicated by a black filled circle. (TIFF 1350 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Laboratorial Science and Technology, School of Public HealthPeking UniversityBeijingPeople’s Republic of China
  2. 2.Vaccine Research Center, School of Public HealthPeking UniversityBeijingPeople’s Republic of China
  3. 3.The Second Affiliated HospitalZhejiang University School of MedicineHangzhouPeople’s Republic of China
  4. 4.The 7th Medical Center of PLA General HospitalBeijingPeople’s Republic of China
  5. 5.State Key Laboratory of Pathogen and BiosecurityBeijing Institute of Microbiology and EpidemiologyBeijingPeople’s Republic of China
  6. 6.Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food SafetyBeijingPeople’s Republic of China

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