Complete genome analysis of a novel phage GW1 lysing Cronobacter
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A newly identified lytic Cronobacter phage, GW1, was isolated from the Pearl River of Guangzhou, China. GW1 had a double-stranded DNA genome of 39,695 nucleotides with an average GC content of 53.18 %. Among the 49 open reading frames (ORFs) identified, genes for rRNA, tRNA, antibiotic resistance, and virulence factors were not found in the phage genome. The morphology, genomic features, and phylogenetic position of GW1 revealed that it represents a new species in the genus T7virus. This novel lytic Cronobacter phage may provide an alternative for phage therapy and biocontrol against Cronobacter.
This work was supported by grants from the National Natural Science Foundation of China (31601571), the National Key R&D Program of China (2017YFC1601200), Pearl River S&T Nova Program of Guangzhou (201806010062), the Natural Science Foundation of Guangdong Province (2016A030310315), and GDAS’ Special Project of Science and Technology Development (2017GDASCX-0201). All authors read and approved the final manuscript. None of the authors reported a conflict of interest.
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