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First genetic detection and characterization of canine parvovirus from diarrheic dogs in Zambia

  • James Kapiya
  • King S. Nalubamba
  • Evans Kaimoyo
  • Katendi Changula
  • Nozyechi Chidumayo
  • Ngonda Saasa
  • Martin C. Simuunza
  • Ayato Takada
  • Aaron S. Mweene
  • Simbarashe Chitanga
  • Edgar Simulundu
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Abstract

Although canine parvovirus (CPV) causes severe gastroenteritis in dogs globally, information on the molecular epidemiology of the virus is lacking in many African countries. Here, 32 fecal samples collected from diarrheic dogs in Zambia were tested for CPV infection using molecular assays. CPV was detected in 23 samples (71.9%). Genetic characterization revealed the predominance of CPV-2c (91.3%). This finding differs from previous reports in Africa, which indicated that CPV-2a and CPV-2b were most prevalent. Phylogenetically, most Zambian CPVs formed a distinct cluster. This is the first report on the molecular characterization of CPV in Zambia.

Notes

Acknowledgements

This work was supported by the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) and the Japan Agency for Medical Research and Development (AMED)/Japan International Cooperation Agency (JICA) within the framework of the Science and Technology Research Partnership for Sustainable Development (SATREPS).

Compliance with ethical standards

Ethical approval

This article does not contain any studies with animals or humans performed by any of the authors.

Conflict of interest

All the authors declare that they have no competing interests.

Supplementary material

705_2018_4068_MOESM1_ESM.docx (16 kb)
Supplementary material 1 (DOCX 15 kb)

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • James Kapiya
    • 1
    • 2
  • King S. Nalubamba
    • 3
  • Evans Kaimoyo
    • 2
  • Katendi Changula
    • 4
  • Nozyechi Chidumayo
    • 3
  • Ngonda Saasa
    • 1
  • Martin C. Simuunza
    • 1
  • Ayato Takada
    • 1
    • 5
  • Aaron S. Mweene
    • 1
    • 6
  • Simbarashe Chitanga
    • 7
  • Edgar Simulundu
    • 1
  1. 1.Department of Disease Control, School of Veterinary MedicineUniversity of ZambiaLusakaZambia
  2. 2.Department of Biological Sciences, School of Natural SciencesUniversity of ZambiaLusakaZambia
  3. 3.Department of Clinical Studies, School of Veterinary MedicineUniversity of ZambiaLusakaZambia
  4. 4.Department of Paraclinical Studies, School of Veterinary MedicineUniversity of ZambiaLusakaZambia
  5. 5.Division of Global EpidemiologyHokkaido University Research Center for Zoonosis ControlSapporoJapan
  6. 6.Africa Center of Excellence for Infectious Diseases of Humans and AnimalsLusakaZambia
  7. 7.Department of Biomedical Sciences, School of Health SciencesUniversity of ZambiaLusakaZambia

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