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Genetic characterization of a new astrovirus in goslings suffering from gout

  • Meiling Jin
  • Xiaoyan Wang
  • Kang Ning
  • Ning Liu
  • Dabing Zhang
Brief Report

Abstract

Since early 2016, the Chinese goose industry has experienced severe outbreaks of gout; however, the etiological factor of the disease is still unclear. Here, we investigated the possible involvement of viral infection in the disease. Using sequence-independent PCR amplification, astrovirus sequences were generated from a gout case. Full-length genomic sequencing and sequence analysis of three goose astrovirus (GoAstV) strains revealed that they belong to a new avastrovirus most closely related to viruses classified within species Avastrovirus 3. The GoAstV was detected in 16/16 gout cases collected from two provinces, supporting a pathogenic role for the new avastrovirus.

Notes

Funding

This study was funded by the China Agriculture Research System (CARS-42-16).

Compliance with ethical standards

Conflict of interest

Meiling Jin declares that she has no conflict of interest. Xiaoyan Wang declares that she has no conflict of interest. Ning Kang declares that he has no conflict of interest. Ning Liu declares that she has no conflict of interest. Dabing Zhang declares that he has no conflict of interest.

Ethical approval

All procedures involving sample collection from goslings were approved by the Animal Welfare and Ethical Censor Committee at China Agricultural University and Beijing Administration Committee of Laboratory Animals (Approval ID SYXK [Jing] 2015–0028).

Supplementary material

705_2018_3932_MOESM1_ESM.docx (70 kb)
Supplementary material 1 (DOCX 69 kb)
705_2018_3932_MOESM2_ESM.docx (73 kb)
Supplementary material 2 (DOCX 72 kb)
705_2018_3932_MOESM3_ESM.docx (74 kb)
Supplementary material 3 (DOCX 73 kb)

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Meiling Jin
    • 1
  • Xiaoyan Wang
    • 1
  • Kang Ning
    • 1
  • Ning Liu
    • 1
  • Dabing Zhang
    • 1
  1. 1.Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary MedicineChina Agricultural UniversityBeijingPeople’s Republic of China

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