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Archives of Virology

, Volume 163, Issue 10, pp 2805–2810 | Cite as

Whole genome analysis of a novel neurotropic bovine astrovirus detected in a Japanese black steer with non-suppurative encephalomyelitis in Japan

  • Yoshimasa Hirashima
  • Daisuke Okada
  • Shoichi Shibata
  • Shu Yoshida
  • Shoichiro Fujisono
  • Tsutomu Omatsu
  • Tetsuya Mizutani
  • Makoto Nagai
Brief Report

Abstract

While neurotropic bovine astroviruses (BoAstVs) have been identified in North America and Europe, their presence has never been reported in Asia. In this study, we detected BoAstV in the brain of a steer showing neurological signs. Phylogenetic analysis revealed that the identified virus belongs to the Virginia/Human-Mink-Ovine clade, which contains most of the neurotropic astroviruses including the neurotropic BoAstVs. Similarity plot analysis showed that the virus was closely related to the American BoAstV NeuroS1 strain with respect to the ORF regions and to the European BoAstV CH13 strain in the 3′ untranslated region, suggesting the occurrence of intra-genotypic recombination events.

Notes

Acknowledgements

We thank to Mr. Kazutoshi Matsuzaki for his kind cooperation in the field research. This work was supported by JSPS KAKENHI Grant number 15K07718.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Research involving human participants and/or animals

The present study was carried out according to the Fundamental Guidelines for Proper Conduct of Animal Experiments and Related Activities in Academic Research Institutions under the jurisdiction of the Ministry of Education, Culture, Sports, Science and Technology of Japan.

Supplementary material

705_2018_3898_MOESM1_ESM.xlsx (11 kb)
Supplementary material 1 (XLSX 10 kb)
705_2018_3898_MOESM2_ESM.ppt (296 kb)
Supplementary material 2 (PPT 298 kb)
705_2018_3898_MOESM3_ESM.ppt (520 kb)
Supplementary material 3 (PPT 522 kb)

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Kagoshima Central Livestock Hygiene Service CenterHiokiJapan
  2. 2.Aira Livestock Hygiene Service CenterKajikiJapan
  3. 3.Nansatsu Livestock Hygiene Service CenterMinamikyushuJapan
  4. 4.Research and Education Center for Prevention of Global Infectious Diseases of AnimalTokyo University of Agriculture and TechnologyFuchuJapan
  5. 5.Department of Bioproduction ScienceIshikawa Prefectural UniversitySuematsuJapan

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