Adenovirus infection in savanna chimpanzees (Pan troglodytes schweinfurthii) in the Issa Valley, Tanzania
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Adenoviruses are a widespread cause of diverse human infections with recently confirmed zoonotic roots in African great apes. We focused on savanna-dwelling chimpanzees in the Issa Valley (Tanzania), which differ from those from forested sites in many aspects of behavior and ecology. PCR targeting the DNA polymerase gene detected AdV in 36.7% (69/188) of fecal samples. We detected five groups of strains belonging to the species Human mastadenovirus E and two distinct groups within the species Human mastadenovirus C based on partial hexon sequence. All detected AdVs from the Issa Valley are related to those from nearby Mahale and Gombe National Parks, suggesting chimpanzee movements and pathogen transmission.
We thank the Tanzanian Wildlife Research Institute (TAWIRI) and Tanzanian Commission for Science and Technology (COSTECH) for permission to conduct research in Tanzania. This research was carried out under the project CEITEC 2020 (LQ1601) with financial support from the Ministry of Education, Youth and Sports of the Czech Republic under the National Program of Sustainability II, by project LO1218 with financial support from the Ministry of Education, Youth and Sports of the Czech Republic under the NPU I programme, and further co-financed from the European Social Fund and the state budget of the Czech Republic (project OPVK CZ.1.07/2.3.00/20.0300). We acknowledge a grant for the Development of Research Organization (RVO: RO0516). Support for the Ugalla Primate Project and ongoing work at Issa comes from the UCSD/Salk Center for Academic Research and Training in Anthropogeny (CARTA). We also thank Klára Petrželková for assistance in the initial stage of project ideas and sampling design.
Compliance with ethical standards
All grants funding this study are listed in the Acknowledgment section.
Conflict of interest
All authors declare that he/she has no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
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