Here, we report the genome sequence of a feral pigeon alphaherpesvirus (columbid herpesvirus type 1, CoHV-1), strain HLJ, and compare it with other avian alphaherpesviruses. The CoHV-1 strain HLJ genome is 204,237 bp in length and encodes approximately 130 putative protein-coding genes. Phylogenetically, CoHV-1 complete genome resides in a monophyletic group with the falconid herpesvirus type 1 (FaHV-1) genome, distant from other alphaherpesviruses. Interestingly, the evolutionary analysis of partial genes of CoHV-1 isolated from different organisms and areas (currently accessible on GenBank) indicates that the CoHV-1 HLJ strain isolated from pigeon (Columba livia) is closely related to the strains isolated from peregrine falcon (Falco peregrinus) in Poland and owl (Bubo virginianus) in USA. These results may suggest possible transmission of the virus between different organisms and different geographic areas.
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Compliance with ethical standards
Conflict of interest
The authors declare no financial or personal relationships with other people or organizations that could inappropriately influence or bias the content of this paper.
All procedures used in this study were approved by the Institution Animal Care and Use Committee of Northeast Forestry University (UT-17; 25 July 2012).
This study was provided by the National Natural Science Foundation of China (Grant No. 31672619), the Fundamental Research Funds for the Central Universities (Grant No. 2572016EAJ5) and the Natural Science Foundation of Heilongjiang Province (Grant No. C2015061).
Supplementary Figure 1: Genetic organization of the CoHV-1 genome. This map shows the class E genome structure of CoHV-1 and indicates the location, direction and sizes of annotated ORFs, numbered based on the CoHV-1 locus tag and labeled according to homology with the characterized HHV-1 genome as well as other avian herpesviruses. The genomic genes were numbered from 5’ to 3’ accordant with the direction of the black arrows in the map. (TIFF 6115 kb)
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