Archives of Virology

, Volume 162, Issue 5, pp 1381–1385 | Cite as

Reintroduction of highly pathogenic avian influenza A/H5N8 virus of clade 2.3.4.4. in Russia

  • Vasiliy Y. Marchenko
  • Ivan M. Susloparov
  • Andrey B. Komissarov
  • Artem Fadeev
  • Nataliya I. Goncharova
  • Andrey V. Shipovalov
  • Svetlana V. Svyatchenko
  • Alexander G. Durymanov
  • Tatyana N. Ilyicheva
  • Lyudmila K. Salchak
  • Elena P. Svintitskaya
  • Valeriy N. Mikheev
  • Alexander B. Ryzhikov
Brief Report

Abstract

In the spring of 2016, a loss of wild birds was observed during the monitoring of avian influenza virus activity in the Republic of Tyva. That outbreak was caused by influenza H5N8 virus of clade 2.3.4.4. In the fall, viruses of H5N8 clade 2.3.4.4 were propagated in European countries. This paper presents some results of analysis of the virus strains isolated during the spring and fall seasons in 2016 in the Russian Federation. The investigated strains were highly pathogenic for mice, and some of their antigenic and genetic features differed from those of an H5N8 strain that circulated in 2014 in Russia.

Keywords

Influenza H5N8 Virus Oseltamivir Avian Influenza Virus Wild Bird 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgements

The authors thank Dr. Richard Webby (St. Jude Children’s Research Hospital, Memphis, TN) for providing the reference antigens and sera. We thank Andrey Varkentin and Yuriy Lobkov (Federal Centre for Animal Health, Vladimir, Russia) for assistance in sample collection. Construction of the tree was done using HA gene sequences deposited in GISAID. We are grateful to GISAID’s EpiFlu™ Database (http://www.gisaid.org) and to the authors who provided sequence information.

Compliance with ethical standards

Funding

This study was funded by RFBR through research project No. 16-34-60073 mol_a_dk. Phylogenic analysis was partially supported by Russian Science Foundation Grant 15-15-00047.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All applicable international, national and institutional guidelines for the care and use of animals were followed. This article does not contain any studies with human participants performed by any of the authors.

References

  1. 1.
    Lee YJ, Kang HM, Lee EK, Song BM, Jeong J, Kwon YK et al (2014) Novel reassortant influenza A(H5N8) viruses, South Korea, 2014. Emerg infect Dis 20(6):1087–1089CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Kim YI, Pascua PN, Kwon HI, Lim GJ, Kim EH, Yoon SW et al (2014) Pathobiological features of a novel, highly pathogenic avian influenza A(H5N8) virus. Emerg Microbes Infect 3(10):e75CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Pulit-Penaloza JA, Sun X, Creager HM, Zeng H, Belser JA, Maines TR, Tumpey TM (2015) Pathogenesis and transmission of novel highly pathogenic avian influenza H5N2 and H5N8 viruses in ferrets and mice. J Virol 89(20):10286–10293CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Wang X, Meng F, Wang D, Liu X, Chen S, Qin T et al (2016) Characteristics of two highly pathogenic avian influenza H5N8 viruses with different pathogenicity in mice. Arch Virol. doi: 10.1007/s00705-016-3043-0 Google Scholar
  5. 5.
    Zhao K, Gu M, Zhong L, Duan Z, Zhang Y, Zhu Y et al (2013) Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China. Vet Microbiol 163(3–4):351–357CrossRefPubMedGoogle Scholar
  6. 6.
    Verhagen JH, Herfst S, Fouchier RAM (2015) How a virus travels the world. Science 347(6222):616–617CrossRefPubMedGoogle Scholar
  7. 7.
    Ramey AM, Reeves AB, TeSlaa JL, Nashold S, Donnelly T, Bahl J, Hall JS (2016) Evidence for common ancestry among viruses isolated from wild birds in Beringia and highly pathogenic intercontinental reassortant H5N1 and H5N2 influenza A viruses. Infect Genet Evol 40:176–185CrossRefPubMedGoogle Scholar
  8. 8.
    Marchenko VY, Susloparov IM, Kolosova NP, Goncharova NI, Shipovalov AV, Durymanov AG et al (2015) Influenza A(H5N8) virus isolation in Russia, 2014. Arch Virol 160(11):2857–2860CrossRefPubMedGoogle Scholar
  9. 9.
    World Organisation for Animal Health (OIE) (2016) Update on highly pathogenic avian influenza in animals (type H5 and H7). OIE, Paris. http://www.oie.int/animal-health-in-the-world/update-on-avian-influenza/2016/. Accessed 29 Dec 2016Google Scholar
  10. 10.
    Marchenko VY, Susloparov IM, Shipovalov AV, Mikheev VN, Ryzhikov AB (2016) Circulation of highly pathogenic avian flu virus in the Russian Federation in 2014–2015. Probl Osobo Opas Infekt (Probl Part Danger Infect) 1:48–54 (in Russian). doi:10.21055/0370-1069-2016-1-48-54Google Scholar
  11. 11.
    Lee DH, Sharshov K, Swayne DE, Kurskaya O, Sobolev I, Kabilov M et al (2017) Novel reassortant clade 2.3.4.4 avian influenza A(H5N8) virus in wild aquatic birds, Russia, 2016. Emerg Infect Dis (cited 08.01.2016). doi: 10.3201/eid2302.161252Google Scholar
  12. 12.
    Yamada S, Suzuki Y, Suzuki T, Le MQ, Nidom CA, Sakai-Tagawa Y et al (2006) Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors. Nature. 444(7117):378–382CrossRefPubMedGoogle Scholar
  13. 13.
    Forbes N, Selman M, Pelchat M, Jia JJ, Stintzi A, Brown EG (2013) Identification of adaptive mutations in the influenza A virus non-structural 1 gene that increase cytoplasmic localization and differentially regulate host gene expression. PLoS One 8(12):e84673CrossRefPubMedPubMedCentralGoogle Scholar
  14. 14.
    Tang JW, Ngai KL, Wong JC, Lam WY, Chan PK (2008) Emergence of adamantane-resistant influenza A(H3N2) viruses in Hong Kong between 1997 and 2006. J Med Virol 80(5):895–901CrossRefPubMedGoogle Scholar
  15. 15.
    Miotto O, Heiny AT, Tan TW, Thomas August J, Brusic V (2008) Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis. BMC Bioinform 9(Suppl 1):S18 (published online 13 Feb 2008) Google Scholar
  16. 16.
    Veen J, Yurlov AK, Delany SN, Mihantiev AI, Selivanova MA, Boere GC (2005) An atlas of movements of Southwest Siberian waterbirds. Wetlands Int. http://www.wetlands.org/Portals/0/publications/Analyses/West%20Siberia%20flyway.pdf
  17. 17.
    Marchenko VY, Susloparov IM, Kolosova NP, Goncharova NI, Shipovalov AV, Ilyicheva TN (2016) Highly pathogenic influenza H5N1 virus of clade 2.3.2.1c in Western Siberia. Arch Virol 161(6):1645–1649CrossRefPubMedGoogle Scholar
  18. 18.
    Sharshov K, Silko N, Sousloparov I, Zaykovskaya A, Shestopalov A, Drozdov I (2010) Avian influenza (H5N1) outbreak among wild birds, Russia, 2009. Emerg Infect Dis 16(2):349–351CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag Wien 2017

Authors and Affiliations

  • Vasiliy Y. Marchenko
    • 1
  • Ivan M. Susloparov
    • 1
  • Andrey B. Komissarov
    • 2
  • Artem Fadeev
    • 2
  • Nataliya I. Goncharova
    • 1
  • Andrey V. Shipovalov
    • 1
  • Svetlana V. Svyatchenko
    • 1
  • Alexander G. Durymanov
    • 1
  • Tatyana N. Ilyicheva
    • 1
  • Lyudmila K. Salchak
    • 3
  • Elena P. Svintitskaya
    • 4
  • Valeriy N. Mikheev
    • 1
  • Alexander B. Ryzhikov
    • 1
  1. 1.State Research Center of Virology and Biotechnology VectorNovosibirskRussian Federation
  2. 2.Research Institute of InfluenzaSaint PetersburgRussian Federation
  3. 3.Tyva Republic Regional office of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor)KyzylRussian Federation
  4. 4.Hygienic and Epidemiological center of Tyva RepublicKyzylRussian Federation

Personalised recommendations