Archives of Virology

, Volume 161, Issue 3, pp 605–612 | Cite as

Evidence for genetic variation of Eurasian avian influenza viruses of subtype H15: the first report of an H15N7 virus

  • Denys Muzyka
  • Mary Pantin-Jackwood
  • Elke Starick
  • Sasan Fereidouni
Original Article

Abstract

Since the first detection of H15 avian influenza viruses (AIVs) in Australia in 1979, only seven H15 strains have been reported. A new H15 AIV was detected in Ukraine in 2010, carrying the unique HA-NA subtype combination H15N7. This virus replicated efficiently in chicken eggs, and antisera against it reacted strongly with the homologous antigen, but with lower titers when using the reference Australian antigen. The amino acid motifs of the HA cleavage site and receptor-binding site were different from those in the Australian viruses. The new virus, together with an H15 virus from Siberia from 2008, constitutes a new clade of H15 AIV isolates.

References

  1. 1.
    Commission of European Communities (CEC) (2006) Commission Decision 2006/437/EC approving a diagnostic manual for avian influenza as provided for in Council Directive 2005/94/EC. Off J Eur Commun 237:1–27Google Scholar
  2. 2.
    Fereidouni SR, Starick E, Grund C, Globig A, Mettenleiter TC, Beer M, Harder T (2009) Rapid molecular subtyping by reverse transcription polymerase chain reaction of the neuraminidase gene of influenza A viruses. Vet Microbiol 135:253–260CrossRefPubMedGoogle Scholar
  3. 3.
    Fereidouni SR, Werner O, Starick E, Beer M, Harder TC, Aghakhan M, Modirrousta H, Amini H, Moghaddam MK, Bozorghmehrifard MH, Akhavizadegan MA, Gaidet N, Newman SH, Hammoumi S, Cattoli G, Globig A, Hoffmann B, Sehati ME, Masoodi S, Dodman T, Hagemeijer W, Mousakhani S, Mettenleiter TC (2010) Avian influenza virus monitoring in wintering water birds in Iran, 2003–2007. Virol J 7:43PubMedCentralCrossRefPubMedGoogle Scholar
  4. 4.
    Gao S, Wang S, Cao S, Sun L, Li J, Bi Y, Gao GF, Liu W (2014) The characteristics of nucleocytoplasmic transport of H1N1 influenza A viruses nuclear export protein (NEP). J Virol 88:7455–7463PubMedCentralCrossRefPubMedGoogle Scholar
  5. 5.
    Haynes L, Arzey E, Bell C, Buchanan N, Burgess G, Cronan V, Dickason C, Field H, Gibbs S, Hansbro P, Hollingsworth T, Hurt A, Kirkland P, McCracken H, O’Connor J, Tracey J, Wallner J, Warner S, Woods R, Bunn C (2009) Australian surveillance for avian influenza viruses in wild birds between July 2005 and June 2007. Aust Vet J 87:266–272CrossRefPubMedGoogle Scholar
  6. 6.
    Hoffmann E, Stech J, Guan Y, Webster RG, Perez DR (2001) Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol 146:2275–2289CrossRefPubMedGoogle Scholar
  7. 7.
    Jagger BW, Wise HM, Kash JC, Walters KA, Wills NM, Xiao YL, Dunfee RL, Schwartzmann LM, Ozinsky A, Bell GL, Dalton RM, Lo A, Efstathiou S, Atkins JF, Firth AE, Taubenberger JK, Digard P (2012) An overlapping protein-coding region in influenza A virus segment 3 modulates the host response. Science 337:199–204PubMedCentralCrossRefPubMedGoogle Scholar
  8. 8.
    Krauss S, Walker D, Pryor SP, Niles L, Chenghong L, Hinshaw VS, Webster RG (2004) Influenza A viruses of migrating wild aquatic birds in North America. Vector Borne Zoonotic Dis 4:177–189CrossRefPubMedGoogle Scholar
  9. 9.
    Mackenzie JS, Edwards EC, Holmes RM, Hinshaw VS (1984) Isolation of ortho- and paramyxoviruses from wild birds in Western Australia, and the characterisation of novel influenza A viruses. Aust J Exp Biol Med Sci 62:89–99CrossRefPubMedGoogle Scholar
  10. 10.
    Mertens E, Dugan VG, Stockwell TB, Lindsay LL, Plancarte M, Boyce WM (2013) Evaluation of phenotypic markers in full genome sequences of avian influenza isolates from California. Comp Immunol Microbiol Infect Dis 36:521–536CrossRefPubMedGoogle Scholar
  11. 11.
    Muzyka D, Pantin-Jackwood M, Spackman E, Stegniy B, Rula O, Shutchenko P (2012) Avian influenza virus wild bird surveillance in the Azov and Black Sea regions of Ukraine (2010–2011). Avian Dis 56:1010–1016CrossRefPubMedGoogle Scholar
  12. 12.
    Obenauer JC, Denson J, Perdeep KM, Su X, Mukatira S, Finkelstein DB, Xu X, Wang J, Ma J, Fan Y, Rakestraw KM, Webster RG, Hoffmann E, Krauss S, Zheng J, Zhang Z, Naeve CE (2006) Large-scale sequence analysis of avian influenza viruses. Science 311:1576–1580CrossRefPubMedGoogle Scholar
  13. 13.
    Onishchenko GG, Berezhnov SP, Shestopalov AM, Alekseev AI, Ternovoi VA, Khaitovich AB, Kroviakova MT, Netesov SV, Drozdov IG (2007) Molecular-biologic analysis of avian influenza virus isolates which caused epizootics on the south of West Siberia and in Crimea. Zh Mikrobiol Epidemiol Immunobiol 5:28–32PubMedGoogle Scholar
  14. 14.
    Pasick J, Pedersen J, Hernandez MS (2012) Avian influenza in North America, 2009–2011. Avian Dis 56:845–848CrossRefPubMedGoogle Scholar
  15. 15.
    Phipps LP, Essen SC, Brown IH (2004) Genetic subtyping of influenza A viruses using RT-PCR with a single set of primers based on conserved sequences within the HA2 coding region. J Virol Methods 122:119–122CrossRefPubMedGoogle Scholar
  16. 16.
    Röhm C, Zhou N, Süss J, Mackenzie J, Webster RG (1996) Characterisation of a novel influenza hemagglutinin, H15: criteria for determination of influenza A subtypes. Virology 217:508–516CrossRefPubMedGoogle Scholar
  17. 17.
    Sivay MV, Baranovich T, Marchenko VY, Sharshov KA, Govorkova EA, Shestopalov AM, Webby RJ (2013) Influenza A (H15N4) virus isolation in Western Siberia, Russia. J Virol 87:3578–3582PubMedCentralCrossRefPubMedGoogle Scholar
  18. 18.
    Slavec B, Krapez U, Racnik AJ, Hari A, Wernig JM, Dovc A, Zadravec M, Lindtner-Knific R, Marhold C, Zorman-Rojs O (2012) Surveillance of influenza A viruses in wild birds in Slovenia from 2006 to 2010. Avian Dis 56:999–1005CrossRefPubMedGoogle Scholar
  19. 19.
    Spackman, E (2008) Avian influenza virus. In: Methods in molecular biology, vol 436. Humana Press, TotowaGoogle Scholar
  20. 20.
    Swayne DE (2008) Avian influenza. Blackwell Publishing, AmesCrossRefGoogle Scholar
  21. 21.
    Verhagen JH, Majoor F, Lexmond P, Vuong O, Kasemir G, Lutterop D, Osterhaus AD, Fouchier RA, Kuiken T (2014) Epidemiology of influenza A virus among black-headed gulls, the Netherlands, 2006–2010. Emerg Infect Dis 20:138–141PubMedCentralCrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Wien 2015

Authors and Affiliations

  • Denys Muzyka
    • 1
  • Mary Pantin-Jackwood
    • 2
  • Elke Starick
    • 3
  • Sasan Fereidouni
    • 3
    • 4
    • 5
  1. 1.National Scientific Center, Institute of Experimental and Clinical Veterinary MedicineKharkivUkraine
  2. 2.Southeast Poultry Research LaboratoryAgricultural Research Service, USDAAthensUSA
  3. 3.Friedrich Loeffler InstituteGreifswaldGermany
  4. 4.WESCA Wildlife NetworkGreifswaldGermany
  5. 5.University of Veterinary Medicine Vienna, Research Institute of Wildlife EcologyViennaAustria

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