Archives of Virology

, Volume 160, Issue 10, pp 2595–2601 | Cite as

Molecular characterization of a reassortant H11N9 subtype avian influenza virus isolated from a domestic duck in Eastern China

  • Haibo Wu
  • Xiuming Peng
  • Xiaorong Peng
  • Nanping Wu
Brief Report


During surveillance for avian influenza viruses (AIVs) in live-poultry markets in Eastern China in 2013, an H11N9 AIV was isolated from a domestic duck. Phylogenetic analysis showed that this strain received its genes from H11, H3, H10, and H7 AIVs of poultry in China. This strain was found to be minimally pathogenic in mice and was able to replicate in mice without prior adaptation. Considering that the reassorted H11N9 viruses were isolated from domestic ducks in this study, it is possible that these ducks play an important role in the generation of novel reassorted H11 AIVs.


Avian influenza viruses Subtype H11N9 Domestic ducks Reassortment 



This study was supported by grants from the National Key Technologies R&D Programme for the 12th Five-Year Plan of China (2012ZX1000-004-005), Zhejiang Provincial Natural Science Foundation of China (Y15H190006), and the Independent Task of State Key Laboratory for Diagnosis and Treatment of Infectious Diseases (Nos.2010ZZ04 and 2014ZZ12).

Supplementary material

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Supplementary material 1 (DOC 850 kb)
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Supplementary material 2 (DOC 1021 kb)
705_2015_2528_MOESM3_ESM.doc (32 kb)
Supplementary material 3 (DOC 32 kb)


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Copyright information

© Springer-Verlag Wien 2015

Authors and Affiliations

  • Haibo Wu
    • 1
  • Xiuming Peng
    • 1
  • Xiaorong Peng
    • 1
  • Nanping Wu
    • 1
  1. 1.State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of MedicineZhejiang UniversityHangzhouChina

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