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Archives of Virology

, Volume 159, Issue 7, pp 1765–1770 | Cite as

The genome sequence of a novel simian adenovirus in a chimpanzee reveals a close relationship to human adenoviruses

  • Chenglin Zhou
  • Hua Tian
  • Xiaochun Wang
  • Wei Liu
  • Shixing Yang
  • Quan Shen
  • Yan Wang
  • Bin Ni
  • Shengxia Chen
  • Xingli Fu
  • Rongmei FeiEmail author
  • Wen ZhangEmail author
Brief Report

Abstract

Recently, several reports have revealed that some simian adenoviruses (AdVs) strains show a close relationship to human AdVs. In the present study, a simian AdV strain named SAdV-ch1 was detected in chimpanzees in China, and its complete genome was determined. Phylogenetic analysis revealed SAdV-ch1 clustering in a clade that was separate from all of the other simian AdVs but genetically close to a human AdV strain, HAdV-18 (GenBank no. GU191019), sharing 92.5 % sequence identity with it. Recombination analysis provided evidence that a recombination event had occurred between SAdV-ch1 and HAdV-61 (JF964962), where SAdV-ch1 exchanged partial of its hexon gene segment with HAdV-61, leading to the recombinant HAdV-31 (AM749299).

Keywords

Simian adenovirus Complete genome Phylogenetic analysis 

Notes

Acknowledgement

This work was partly supported by China Postdoctoral Science Foundation No. 2013M531291 and 2013M530234, the National Natural Science Foundation of China No. 31302107, the Ph.D. Programs Foundation of the Ministry of Education of China No. 20113227120008, the Natural Science Foundation of Jiangsu Province no. BK2012289, the Special Fund for Preventive Medicine of Jiangsu Province no. Y2012067, and the Professional Research Foundation for Advanced Talents of Jiangsu University under grant no.12JDG085.

Supplementary material

705_2013_1967_MOESM1_ESM.docx (14 kb)
Supplementary material 1 (DOCX 13 kb)

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Copyright information

© Springer-Verlag Wien 2014

Authors and Affiliations

  • Chenglin Zhou
    • 1
    • 2
  • Hua Tian
    • 3
  • Xiaochun Wang
    • 1
  • Wei Liu
    • 4
  • Shixing Yang
    • 1
  • Quan Shen
    • 1
  • Yan Wang
    • 1
  • Bin Ni
    • 1
  • Shengxia Chen
    • 1
  • Xingli Fu
    • 1
  • Rongmei Fei
    • 5
    Email author
  • Wen Zhang
    • 1
    Email author
  1. 1.School of Medical Science and Laboratory MedicineJiangsu UniversityZhenjiangChina
  2. 2.Department of Laboratory MedicineThe First People’s Hospital of SuqianSuqianChina
  3. 3.Jiangsu Provincial Center for Disease Prevention and ControlNanjingChina
  4. 4.Department of MicrobiologyUniversity of Pennsylvania Perelman School of MedicinePhiladelphiaUSA
  5. 5.College of Veterinary MedicineNanjing Agricultural UniversityNanjingChina

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