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Archives of Virology

, Volume 157, Issue 11, pp 2253–2255 | Cite as

Tick-borne encephalitis virus in Eastern Siberia: complete genome characteristics

  • Nina V. Kulakova
  • Evgenii I. Andaev
  • Sergei I. Belikov
Annotated Sequence Record

Abstract

Tick-borne encephalitis (TBE) is one of the most important arboviral diseases across Eurasia. TBE virus (TBEV) is transmitted by tick bite and causes a potentially fatal neurological infection in humans. In the Russian Federation, TBE is endemic in most regions, with 3000-5000 cases of the disease annually. To characterise TBEV in Eastern Siberia, the complete genomes of five TBEV isolates from patients with different clinical manifestations were sequenced. The results show that the Siberian and Far Eastern subtypes of TBEV cause the disease in people in Eastern Siberia. Complete genome analysis revealed an unexpectedly high genetic variability within the Siberian subtype.

Keywords

Siberian Group Translate Amino Acid Sequence DTCS Quick Start TBEV Strain Distinct Phylogenetic Lineage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Ackowledgments

This work was funded by International Science and Technology Center project No. 4006.

Supplementary material

705_2012_1412_MOESM1_ESM.pdf (188 kb)
Supplementary material 1 (PDF 188 kb)
705_2012_1412_MOESM2_ESM.pdf (169 kb)
Supplementary material 2 (PDF 168 kb)
705_2012_1412_MOESM3_ESM.pdf (327 kb)
Supplementary material 3 (PDF 327 kb)

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Nina V. Kulakova
    • 1
  • Evgenii I. Andaev
    • 2
  • Sergei I. Belikov
    • 1
  1. 1.Laboratory of Analytical and Bioorganic ChemistryLimnological Institute of SB RASIrkutskRussia
  2. 2.Laboratory of Natural Focal Viruses InfectionIrkutsk Antiplague Research Institute of Siberia and Far EastIrkutskRussia

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