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Archives of Virology

, Volume 157, Issue 2, pp 329–332 | Cite as

Risk factors associated with hepatitis C virus infection in an urban population of the State of Mexico

  • S. Romero-FigueroaEmail author
  • E. Ceballos-Salgado
  • L. Santillán-Arreygue
  • M. Miranda-García
  • M. Rubio-Lezama
  • J. J. Garduño-García
Brief Report

Abstract

The aim of this study was to determine the seroprevalence anti-hepatitis C virus (HCV) antibodies and risk factors associated with patients attending primary-care clinics in the State of Mexico. A cross-sectional, prospective study was conducted on 10,524 consenting patients with history of at least one risk factor for HCV. Antibodies were detected by immunoassay, third-generation ELISA; RT-PCR was carried out to confirm HCV infection. The seroprevalence of HCV antibodies was 1.2% (128). The most common risk factor was blood transfusion prior to 1993 (56.3%), followed by family history of cirrhosis 29 (22.7%); tattoos and/or piercings, 28 (21.9%); high-risk sexual practices, 4 (3.1%); healthcare work, 8 (6.3%); and intravenous drug use, 1 (8%). RT-PCR was performed on samples from 83 patients. Forty-five were considered positive. Genotype 1a was the most prevalent (37.7%).

Keywords

Blood Transfusion Reverse Transcriptase Polymerase Chain Reaction Common Risk Factor Perinatal Transmission Active Viremia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • S. Romero-Figueroa
    • 1
    Email author
  • E. Ceballos-Salgado
    • 2
  • L. Santillán-Arreygue
    • 1
  • M. Miranda-García
    • 3
  • M. Rubio-Lezama
    • 1
  • J. J. Garduño-García
    • 1
  1. 1.Health Research Coordination Office, Mexico Western Regional OfficeMexican Institute of Social SecurityTolucaMéxico
  2. 2.Family Medical Unit 222, Research and Education Coordination Office, Mexico Western Regional OfficeMexican Institute of Social SecurityTolucaMéxico
  3. 3.Epidemiology Division, Mexico Western Regional OfficeGeneral Zone Hospital 194, Mexican Institute of Social SecurityTolucaMéxico

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