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Archives of Virology

, Volume 155, Issue 8, pp 1307–1311 | Cite as

Presence of herpesvirus in striped dolphins stranded during the cetacean morbillivirus epizootic along the Mediterranean Spanish coast in 2007

  • Edwige N. Bellière
  • Fernando Esperón
  • Manuel Arbelo
  • María J. Muñoz
  • Antonio Fernández
  • José M. Sánchez-Vizcaíno
Brief Report

Abstract

A screening for herpesvirus (HV) was carried out using a tissue bank obtained from the cetacean morbillivirus (CeMV) mortality episode that occurred along the Mediterranean Spanish coast in 2007. A total of 14 cetaceans, including six long-finned pilot whales and eight striped dolphins, were studied using histopathology and molecular analysis to detect HV and CeMV. In five of the eight dolphins (62.5%) infected with CeMV, eight novel HV sequences were also detected. No HV lesions were found in any of the coinfected dolphins, which may indicate that HV did not contribute to the mortality in the CeMV outbreak. This is the first report of HV infection in any cetacean from the Mediterranean Sea.

Keywords

Bottlenose Dolphin Pilot Whale Beaked Whale Striped Dolphin Mediterranean Spanish Coast 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

We are grateful to Elena Neves and Verónica Nogal for their excellent technical assistance. This work is dedicated to the memory of Professor Tom Barrett (Institute for Animal Health: Pirbright Laboratory, UK), who kindly provided us with the control DMV MUC strain. This work was partially funded by project CGL2009-08125 of the Spanish National Research Plan and by the Agreement INIA-MARM CC08-020.

Conflict of interest statement

The authors declare that they have no conflict of interest.

References

  1. 1.
    Aguilar A, Borrell A (1994) Abnormally high polychlorinated biphenyl levels in striped dolphins (Stenella coeruleoalba) affected by the 1990–1992 Mediterranean epizootic. Sci Total Environ 154:237–247CrossRefPubMedGoogle Scholar
  2. 2.
    Blanchard TW, Santiago NT, Lipscomb TP, Garber RL, McFee WE, Knowles S (2001) Two novel alphaherpesviruses associated with fatal disseminated infections in Atlantic bottlenose dolphins. J Wildl Dis 37:297–305PubMedGoogle Scholar
  3. 3.
    Borrell A, Aguilar A, Corsolini S, Focardi S (1996) Evaluation of toxicity and sex-related variation of PCB levels in Mediterranean striped dolphins affected by an epizootic. Chemosphere 32:2359–2369CrossRefPubMedGoogle Scholar
  4. 4.
    Borrell A, Aguilar A (2007) Organochlorine concentrations declined during 1987–2002 in western Mediterranean bottlenose dolphins, a coastal top predator. Chemosphere 66:347–352CrossRefPubMedGoogle Scholar
  5. 5.
    Di Guardo G, Marruchella G, Agrimi U, Kennedy S (2005) Morbillivirus infections in aquatic mammals: a brief overview. J Vet Med A Physiol Pathol Clin Med 52:88–93PubMedGoogle Scholar
  6. 6.
    Domingo M, Ferrer L, Pumarola M, Marco A, Plana J, Kennedy S, McAliskey M, Rima BK (1990) Morbillivirus in dolphins. Nature 348:21CrossRefPubMedGoogle Scholar
  7. 7.
    Domingo M, Visa J, Pumarola M, Marco AJ, Ferrer L, Rabanal R, Kennedy S (1992) Pathologic and immunocytochemical studies of morbillivirus infection in striped dolphins (Stenella coeruleoalba). Vet Pathol 29:1–10CrossRefPubMedGoogle Scholar
  8. 8.
    Dungworth DL (1993) The respiratory system. In: Jubb JVK, Kennedy PC, Palmer N (eds) Pathology of domestic animals, Academic Press, San Diego, pp 539–699Google Scholar
  9. 9.
    Fenner F, Gibbs E, Murphy F, Rott R, Studdert MJ, White D (1993) Herpesviridae. Veterinary virology. Academic Press Inc, London, pp 301–325Google Scholar
  10. 10.
    Fernandez A, Esperon F, Herraez P, de Los Monteros AE, Clavel C, Bernabe A, Sanchez-Vizcaino JM, Verborgh P, De Stephanis R, Toledano F, Bayon A (2008) Morbillivirus and pilot whale deaths, Mediterranean Sea. Emerg Infect Dis 14:792–794CrossRefPubMedGoogle Scholar
  11. 11.
    Fournier M, Degas V, Colborn T, Omara FO, Denizeau F, Potworowski EF, Brousseau P (2000) Immunosuppression in mice fed on diets containing beluga whale blubber from the St Lawrence estuary and the Arctic populations. Toxicol Lett 112–113:311–317CrossRefPubMedGoogle Scholar
  12. 12.
    Hargis AM, Ginn PE, Mansell JEKL, Garber RL (1999) Ulcerative facial and nasal dermatitis and stomatitis in cats associated with feline herpesvirus 1. Vet Dermatol 10:267–274CrossRefGoogle Scholar
  13. 13.
    Heaney J, Barrett T, Cosby SL (2002) Inhibition of in vitro leukocyte proliferation by morbilliviruses. J Virol 76:3579–3584CrossRefPubMedGoogle Scholar
  14. 14.
    Kannan K, Tanabe S, Borrell A, Aguilar A, Focardi S, Tatsukawa R (1993) Isomer-specific analysis and toxic evaluation of polychlorinated biphenyls in striped dolphins affected by an epizootic in the western Mediterranean sea. Arch Environ Contam Toxicol 25:227–233CrossRefPubMedGoogle Scholar
  15. 15.
    McGeoch DJ, Rixon FJ, Davison AJ (2006) Topics in herpesvirus genomics and evolution. Virus Res 117:90–104CrossRefPubMedGoogle Scholar
  16. 16.
    Raga JA, Banyard A, Domingo M, Corteyn M, Van Bressem MF, Fernandez M, Aznar FJ, Barrett T (2008) Dolphin morbillivirus epizootic resurgence, Mediterranean Sea. Emerg Infect Dis 14:471–473CrossRefPubMedGoogle Scholar
  17. 17.
    Roizmann B, Desrosiers RC, Fleckenstein B, Lopez C, Minson AC, Studdert MJ (1992) The family Herpesviridae: an update. The Herpesvirus Study Group of the International Committee on Taxonomy of Viruses. Arch Virol 123:425–449CrossRefPubMedGoogle Scholar
  18. 18.
    Saliki JT, Cooper EJ, Rotstein DS, Caseltine SL, Pabst DA, McLellan WA, Govett P, Harms C, Smolarek KA, Romero CH (2006) A novel gammaherpesvirus associated with genital lesions in a Blainville’s beaked whale (Mesoplodon densirostris). J Wildl Dis 42:142–148PubMedGoogle Scholar
  19. 19.
    Smolarek Benson KA, Manire CA, Ewing RY, Saliki JT, Townsend FI, Ehlers B, Romero CH (2006) Identification of novel alpha- and gammaherpesviruses from cutaneous and mucosal lesions of dolphins and whales. J Virol Methods 136:261–266CrossRefPubMedGoogle Scholar
  20. 20.
    van Elk CE, van de Bildt MW, de Jong AA, Osterhaus AD, Kuiken T (2009) Herpesvirus in bottlenose dolphins (Tursiops truncatus): cultivation, epidemiology, and associated pathology. J Wildl Dis 45:895–906PubMedGoogle Scholar
  21. 21.
    VanDevanter DR, Warrener P, Bennett L, Schultz ER, Coulter S, Garber RL, Rose TM (1996) Detection and analysis of diverse herpesviral species by consensus primer PCR. J Clin Microbiol 34:1666–1671PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Edwige N. Bellière
    • 1
  • Fernando Esperón
    • 1
  • Manuel Arbelo
    • 2
  • María J. Muñoz
    • 1
  • Antonio Fernández
    • 2
  • José M. Sánchez-Vizcaíno
    • 3
  1. 1.National Institute for Agricultural and Food Research and TechnologyValdeolmosSpain
  2. 2.Institute of Animal HealthUniversity of Las Palmas de Gran CanariaLas PalmasSpain
  3. 3.Complutense University of MadridMadridSpain

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