Archives of Virology

, Volume 155, Issue 4, pp 525–533 | Cite as

Predominance of rotavirus G2P[4] and emergence of G12P[9] strains in Asunción, Paraguay, 2006–2007

  • Magaly Martínez
  • Alberto A. Amarilla
  • Maria E. Galeano
  • Victor H. Aquino
  • Norma Fariña
  • Graciela Russomando
  • Gabriel I. Parra
Original Article

Abstract

Rotavirus is the most common cause of severe diarrhea in children worldwide. Monitoring the diversity of rotavirus strains is of great importance for current and future vaccination programs. To determine the diversity of rotavirus circulating in Asuncion, Paraguay, between 2006 and 2007, we carried out a molecular characterization of rotaviruses detected in children <5 years old and adults (>18 years old). We found that the most common circulating strain was G2P[4] (69/143), followed by G9P[8] (37/143). The temporal distribution of strains showed that, in children, G2P[4] was predominant in 2006, and that G2P[4] and G9P[8] were co-predominant in 2007, whereas in adults, G2P[4] was predominant in both years. Additionally, one G9P[6] and three G12P[9] strains were found in adult samples, making this the first report of these strains circulating in Paraguay. Sequence analysis of the G12P[9] strains suggests across-border migration of this strain within the southern cone of America.

Supplementary material

705_2010_617_MOESM1_ESM.doc (55 kb)
Supplementary material 1 (DOC 55 kb)

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Magaly Martínez
    • 1
  • Alberto A. Amarilla
    • 1
    • 2
  • Maria E. Galeano
    • 1
  • Victor H. Aquino
    • 2
    • 5
  • Norma Fariña
    • 1
    • 3
  • Graciela Russomando
    • 1
  • Gabriel I. Parra
    • 1
    • 4
  1. 1.Molecular Biology Department, IICSNational University of AsuncionAsunciónParaguay
  2. 2.Virology Research CenterRibeirão Preto School of Medicine, USPRibeirão PretoBrazil
  3. 3.Clinical Laboratory of San Roque Private HospitalAsunciónParaguay
  4. 4.Laboratory of Infectious DiseasesNIAID, National Institute of HealthBethesdaUSA
  5. 5.Clinical, Toxicological and Bromatological Department, Faculty of Pharmaceutical Sciences of Ribeirão PretoUSPRibeirão PretoBrazil

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