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Archives of Virology

, Volume 154, Issue 6, pp 909–918 | Cite as

Hytrosaviridae: a proposal for classification and nomenclature of a new insect virus family

  • Adly M. M. Abd-Alla
  • J. M. Vlak
  • M. Bergoin
  • J. E. Maruniak
  • A. Parker
  • J. P. Burand
  • J. A. Jehle
  • D. G. Boucias
  • Hytrosavirus Study Group of the ICTV
Brief Review

Abstract

Salivary gland hypertrophy viruses (SGHVs) have been identified from different dipteran species, such as the tsetse fly Glossina pallidipes (GpSGHV), the housefly Musca domestica (MdSGHV) and the narcissus bulbfly Merodon equestris (MeSGHV). These viruses share the following characteristics: (i) they produce non-occluded, enveloped, rod-shaped virions that measure 500–1,000 nm in length and 50–100 nm in diameter; (ii) they possess a large circular double-stranded DNA (dsDNA) genome ranging in size from 120 to 190 kbp and having G + C ratios ranging from 28 to 44%; (iii) they cause overt salivary gland hypertrophy (SGH) symptoms in dipteran adults and partial to complete sterility. The available information on the complete genome sequence of GpSGHV and MdSGHV indicates significant co-linearity between the two viral genomes, whereas no co-linearity was observed with baculoviruses, ascoviruses, entomopoxviruses, iridoviruses and nudiviruses, other large invertebrate DNA viruses. The DNA polymerases encoded by the SGHVs are of the type B and closely related, but they are phylogenetically distant from DNA polymerases encoded by other large dsDNA viruses. The great majority of SGHV ORFs could not be assigned by sequence comparison. Phylogenetic analysis of conserved genes clustered both SGHVs, but distantly from the nudiviruses and baculoviruses. On the basis of the available morphological, (patho)biological, genomic and phylogenetic data, we propose that the two viruses are members of a new virus family named Hytrosaviridae. This proposed family currently comprises two unassigned species, G. pallidipes salivary gland hypertrophy virus and M. domestica salivary gland hypertrophy virus, and a tentative unassigned species, M. equestris salivary gland hypertrophy virus. Here, we present the characteristics and the justification for establishing this new virus family.

Keywords

Virus Family dsDNA Virus Aminoacylase Housefly Musca Domestica Haematobia Irritans 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

We thank Dr. Monique M. van Oers from the Laboratory of Virology, Wageningen University, The Netherlands, for helping in preparation of the gene parity plot figure.

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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Adly M. M. Abd-Alla
    • 1
  • J. M. Vlak
    • 2
  • M. Bergoin
    • 3
  • J. E. Maruniak
    • 4
  • A. Parker
    • 1
  • J. P. Burand
    • 5
  • J. A. Jehle
    • 6
  • D. G. Boucias
    • 4
  • Hytrosavirus Study Group of the ICTV
  1. 1.Entomology Unit, FAO/IAEA Agriculture and Biotechnology LaboratoryIAEA Laboratories SeibersdorfSeibersdorfAustria
  2. 2.Laboratory of VirologyWageningen UniversityWageningenThe Netherlands
  3. 3.Laboratoire de Pathologie ComparéeUniversité Montpellier 2MontpellierFrance
  4. 4.Department of Entomology and NematologyUniversity of FloridaGainesvilleUSA
  5. 5.Department of Plant, Soil and Insect ScienceUniversity of MassachusettsAmherstUSA
  6. 6.Agricultural Service Center Palatinate (DLR Rheinpfalz)WeinstrasseGermany

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