Archives of Virology

, Volume 154, Issue 2, pp 199–207 | Cite as

Complete genome sequence of Nariva virus, a rodent paramyxovirus

  • L. S. Lambeth
  • M. Yu
  • D. E. Anderson
  • G. Crameri
  • B. T. Eaton
  • L.-F. Wang
Original Article


Nariva virus (NarPV) was isolated from forest rodents (Zygodontomys b. brevicauda) in eastern Trinidad in the early 1960s. Initial classification within the family Paramyxoviridae was based mainly on morphological observations including the structure of nucleocapsids and virion surface projections. Here, we report the characterization of the complete genome sequence of NarPV. The genome is 15,276 nucleotides in length, conforming to the rule-of-six, and has a genome organization typical of most members of the family, with six transcriptional units in the order 3′-N–P-M-F–H-L-5′. The gene junctions contain highly conserved gene start and stop signals and a tri-nucleotide intergenic sequence present in most members of the subfamily Paramyxovirinae. Sequence comparison studies indicate that NarPV is most closely related to Mossman virus, which was isolated from wild rats (Rattus leucopus) in Queensland, Australia, in 1970. This study confirmed the classification of NarPV as a member of the subfamily Paramyxovirinae and established the close genome organization and sequence relationship between the two rodent paramyxoviruses isolated almost a decade apart and from two locations separated by more than 15,000 km.


Newcastle Disease Virus Measle Virus Editing Site Canine Distemper Virus cDNA Subtraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We thank Dr. N. Karabatsos for supplying the Nariva virus stock, Kaylene Selleck and Eric Hansson for technical assistance, Tony Pye for providing the automated sequencing service, and Drs. Glenn Marsh and Jackie Pallister for critical review of the manuscript.


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • L. S. Lambeth
    • 1
    • 2
  • M. Yu
    • 1
  • D. E. Anderson
    • 1
    • 3
  • G. Crameri
    • 1
  • B. T. Eaton
    • 1
  • L.-F. Wang
    • 1
  1. 1.CSIRO Livestock Industries, Australian Animal Health LaboratoryGeelongAustralia
  2. 2.Division of MicrobiologyInstitute for Animal HealthComptonUK
  3. 3.INRS-Institut Armand-FrappierUniversité du QuébecLavalCanada

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