Co-circulation of distinct genetic lineages of astroviruses in turkeys and guinea fowl Article First Online: 16 November 2006 Received: 09 March 2006 Accepted: 17 August 2006 DOI:
Cite this article as: Cattoli, G., De Battisti, C., Toffan, A. et al. Arch Virol (2007) 152: 595. doi:10.1007/s00705-006-0862-4 Summary.
Viruses belonging to the genus
Astrovirus have been increasingly associated with enteritis in mammalian and avian species, including turkeys. More recently, astroviruses have also been detected in diseased guinea fowl. In turkeys, two genetically distinct types of astrovirus have been reported, namely turkey astrovirus 1 and 2 (TAstV1 and TAstV2). The prevalence and the pathogenesis of astrovirus infections in this species is currently unknown, with the exception of data generated in the USA. In the present report, we have demonstrated the co-circulation of distinct genetic lineages of astroviruses infecting turkeys and guinea fowl. The predominant lineage infecting turkeys is genetically related to the American TAstV2, but genetic variability within this lineage was demonstrated. Other isolates appeared to be either TastV1-related or unrelated to any other known isolate. Astroviruses infecting guinea fowl were more closely related to TAstV2, and interspecies transmissions between turkeys and guinea fowl is suggested as a possible mechanism by which these viruses may have evolved, based on the genetic data available. This investigation provides genetic and epidemiological information contributing to a better understanding of enteric viral infections in turkeys and guinea fowl. References Barnes, HJ, Guy, JS 2003 Poult enteritis mortality syndrome Saif, YM eds. Diseases of poultry11 Blackwell Ames, IA 320 326 Google Scholar Behling-Kelly, E, Schultz-Cherry, SL, Koci, M, Kelley, L, Larsen, D, Brown, C 2002 Localization of astrovirus in experimentally infected turkeys as determined by in situ hybridisation Vet Pathol 39 595 598 PubMed CrossRef Google Scholar Cattoli, G, Toffan, A, De Battisti, C, Salviato, A, Terregino, C, Capua, I 2005 Astroviruses found in the intestinal contents of guinea fowl suffering from enteritis Vet Rec 12 220 Google Scholar Guy, JS, Miles, AM, Smith, L, Fuller, FJ, Schultz-Cherry, SL 2004 Antigenic and genomic characterization of turkey enterovirus-like virus (North Carolina, 1988 isolate): identification of the virus as turkey astrovirus 2 Avian Dis 48 206 211 PubMed CrossRef Google Scholar Hillis, DM, Bull, JJ 1993 An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis Syst Biol 42 182 192 CrossRef Google Scholar Jonassen, CM, Jonassen, TØ, Grinde, B 1998 A common RNA motif in the 3′ end of the genome of astroviruses, avian infectious bronchitis virus and an equine rhinovirus J Gen Virol 79 715 718 PubMed Google Scholar Jonassen, CM, Jonassen, TØ, Saif, YM, Snodgrass, DR, Ushijima, H, Shimizu, M, Grinde, B 2001 Comparison of capsid sequences from human and animal astroviruses J Gen Virol 82 1061 1067 PubMed Google Scholar Jonassen, CM, Jonassen, TØ, Sveen, TM, Grinde, B 2003 Complete genomic sequence of astroviruses from sheep and turkey: comparison with related viruses Virus Res 91 195 201 PubMed CrossRef Google Scholar Koci, MD, Schultz-Cherry, SL 2002 Avian astroviruses Avian Pathol 31 213 227 PubMed CrossRef Google Scholar Koci, MD, Seal, BS, Schultz-Cherry, SL 2000 Development of an RT-PCR diagnostic test for an avian astrovirus J Virol Methods 90 79 83 PubMed CrossRef Google Scholar
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