Archives of Virology

, Volume 151, Issue 11, pp 2289–2299 | Cite as

Genetic characterization of novel reassortant H1N2 influenza A viruses isolated from pigs in southeastern China

  • X. Qi
  • C. P. Lu
Brief Report


In December 2004, three influenza H1N2 viruses were isolated from lung samples of pigs that had died from respiratory disease on a farm in southeastern China. To determine the genetic characterization and probable origin, one of the three isolates, A/Swine/Zhejiang/1/2004 (Sw/ZJ/1/2004), was genetically analyzed. Sw/ZJ/1/2004 was a reassortant with an NA gene most closely related to the corresponding gene from a human-like H3N2 virus circulating in 1995. The remaining seven genes were most closely related to those from the classical swine H1N1 virus. Sw/ZJ/1/2004 appeared to be a novel reassortant H1N2 virus that was genetically distinguishable from other H1N2 viruses found in pigs worldwide. The isolation of Sw/ZJ/1/2004 provided further evidence for pigs serving as a “mixing vessel” for the generation of new reassortant genotypes of influenza viruses and emphasizes the importance of reinforcing influenza virus surveillance in pigs in China.


H1N2 Virus Avian Virus Reassortant Virus Human H3N2 Virus Reassortant H1N2 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • X. Qi
    • 1
  • C. P. Lu
    • 1
  1. 1.College of Veterinary Medicine, Nanjing Agricultural UniversityNanjingP.R. China

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