Archives of Virology

, Volume 150, Issue 9, pp 1903–1909 | Cite as

Proposal for genetic characterisation of wild-type mumps strains: Preliminary standardisation of the nomenclature

  • L. Jin
  • B. Rima
  • D. Brown
  • C. Örvell
  • T. Tecle
  • M. Afzal
  • K. Uchida
  • T. Nakayama
  • J.-W. Song
  • C. Kang
  • P. A. Rota
  • W. Xu
  • D. Featherstone
Brief Report

Summary.

Though mumps virus (MuV) is a monotypic virus, genetic variation between strains has been described. Viruses have been placed into genotypes designated A–L based on the nucleotide sequence of the small hydrophobic (SH) gene, which is the most variable gene in the mumps genome. Molecular characterisation of MuV is an important component of mumps surveillance because it can help identify the transmission pathways of the virus as well as distinguish between wild-type and vaccine strains. Here, we propose a standardized nomenclature and an analysis protocol for the genetic characterisation of mumps strains to facilitate expansion of molecular epidemiological studies. In addition to assigning standard reference strains for the recognized genotypes of MuV, a convention is proposed for naming for strains and criteria to designate a new genotype.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Afzal, MA, Buchanan, J, Heath, AB, Minor, PD 1997Clustering of mumps virus isolates by SH gene sequence only partially reflects geographical origin.Arch Virol142227238CrossRefPubMedGoogle Scholar
  2. Afzal, MA, Buchanan, J, Dias, JA, Cordeiro, M, Bentley, ML, Shorrock, CA, Minor, PD 1997RT-PCR based diagnosis and molecular characterisation of mumps viruses derived from clinical specimens collected during the 1996 mumps outbreak in Portugal.J Med Virol52349353CrossRefPubMedGoogle Scholar
  3. Carbone KM, Wolinsky JS (2001) Mumps virus. In: Knipe DM, Howley PM (eds), Fields virology, 4th edn, vol 1. Lippincott-Raven, Philadelphia, pp 1381–1400Google Scholar
  4. Forsey, T, Bentley, ML, Minor, PD, Begg, N 1992Mumps vaccines and meningitis.Lancet340980CrossRefGoogle Scholar
  5. Galazka, AM, Robertson, SE, Kraigher, A 1999Mumps and mumps vaccine: a global review.Bull World Health Organ77314PubMedGoogle Scholar
  6. Inou, Y, Nakayama, T, Yoshida, N, Uejima, H, Yuri, K, Kamada, M, Kumagai, T, Sakiyama, H, Miyata, A, Ochiai, H, Ihara, T, Okafuji, T, Okafuji, T, Nagai, T, Suzuki, E, Shimomura, K, Ito, Y, Miyazaki, C 2004Molecular epidemiology of mumps virus in Japan and proposal of two new genotypes.J Med Virol7397104CrossRefPubMedGoogle Scholar
  7. Jin, L, Beard, S, Brown, DW 1999Genetic heterogeneity of mumps virus in the United Kingdom: identification of two new genotypes.J Infect Dis180829833CrossRefPubMedGoogle Scholar
  8. Jin, L, Brown, DWG, Litton, PA, White, JM 2004Genetic diversity of mumps virus in oral fluid specimens: Application to mumps epidemiological study.J Infect Dis18910011008CrossRefPubMedGoogle Scholar
  9. Johansson, B, Tecle, T, Örvell, C 2000Proposed criteria for classification of new genotypes of mumps virus.Scand J Infect Dis34355357CrossRefGoogle Scholar
  10. Kashiwagi, Y, Takami, T, Mori, T, Nakayama, T 1999Sequence analysis of F, SH, and HN genes among mumps virus strains in Japan.Arch Virol144593599CrossRefPubMedGoogle Scholar
  11. Kim, SH, Song, KJ, Shin, YK, Kim, JH, Choi, SM, Park, KS, Baek, LJ, Lee, YJ, Song, JW 2000Phylogenetic analysis of the small hydrophobic (SH) gene of mumps virus in Korea: identification of a new genotype.Microbiol Immunol44173177PubMedGoogle Scholar
  12. Lee, JY, Kim, YY, Shin, GC, Na, BK, Lee, JS, Lee, HD, Kim, JH, Kim, WJ, Kim, J, Kang, C, Cho, HW 2003Molecular characterization of two genotypes of mumps virus circulated in Korea during 1998–2001.Virus Res97111116CrossRefPubMedGoogle Scholar
  13. Örvell, C, Kalantari, M, Johansson, B 1997Characterization of five conserved genotypes of the mumps virus small hydrophobic (SH) protein gene.J Gen Virol789195PubMedGoogle Scholar
  14. Örvell, C, Tecle, T, Johansson, B, Saito, H, Samuelson, A 2002Antigenic relationships between six genotypes of the small hydrophobic protein gene of mumps virus.J Gen Virol8324892496PubMedGoogle Scholar
  15. Ströhle, A, Bernasconi, C, Germann, D 1996A new mumps virus lineage found in the 1995 mumps outbreak in western Switzerland identified by nucleotide sequence analysis of the SH gene.Arch Virol141733741CrossRefPubMedGoogle Scholar
  16. Takahashi, M, Nakayama, T, Kashiwagi, Y, Takami, T, Sonoda, S, Yamanaka, T, Ochiai, H, Ihara, T, Tajima, T 2000Single genotype of measles virus is dominant whereas several genotypes of mumps virus are co-circulating.J Med Virol62278285CrossRefPubMedGoogle Scholar
  17. Tecle, T, Johansson, B, Jejcic, A, Forsgren, M, Örvell, C 1998Characterization of three co-circulating genotypes of the small hydrophobic protein gene of mumps virus.J Gen Virol7929292937PubMedGoogle Scholar
  18. Tecle, T, Bottiger, B, Örvell, C, Johansson, B 2001Characterization of two decades of temporal co-circulation of four mumps virus genotypes in Denmark: identification of a new genotype.J Gen Virol8226752680PubMedGoogle Scholar
  19. Tecle, T, Mickiene, A, Johansson, B, Lindquist, L, Örvell, C 2002Molecular characterisation of two mumps virus genotypes circulating during an epidemic in Lithuania from 1998 to 2000.Arch Virol147243253CrossRefPubMedGoogle Scholar
  20. Uchida, K, Shinohara, M, Shimada, S, Segawa, Y, Hoshino, Y 2001Characterization of mumps virus isolated in Saitama Prefecture, Japan by sequence analysis of the SH gene.Microbiol Immunol45851855PubMedGoogle Scholar
  21. Utz, S, Richard, J-L, Capaul, S, Matter, HC, Hrisoho, MG, Mühlemann, K 2004Phylogenetic analysis of clinical mumps virus isolates from vaccinated and non-vaccinated patients with mumps during an outbreak, Switzerland 1998–2000.J Med Virol739196CrossRefPubMedGoogle Scholar
  22. Wu, L, Bai, Z, Li, Y, Rima, BK, Afzal, MA 1998Wild type mumps viruses circulating in China establish a new genotype.Vaccine16281285CrossRefPubMedGoogle Scholar
  23. Yeo, RP, Afzal, MA, Forsey, T, Rima, BK 1993Identification of a new mumps virus lineage by nucleotide sequence analysis of the SH gene of ten different strains.Arch Virol128371377CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag/Wien 2005

Authors and Affiliations

  • L. Jin
    • 1
  • B. Rima
    • 2
  • D. Brown
    • 1
  • C. Örvell
    • 3
  • T. Tecle
    • 3
  • M. Afzal
    • 4
  • K. Uchida
    • 5
  • T. Nakayama
    • 6
  • J.-W. Song
    • 7
  • C. Kang
    • 8
  • P. A. Rota
    • 9
  • W. Xu
    • 10
  • D. Featherstone
    • 11
  1. 1.Virus Reference DepartmentCentre for Infections, Health Protection AgencyLondonU.K.
  2. 2.Medical Biology Centre, The Queen’s University of BelfastBelfastU.K.
  3. 3.Division of Clinical VirologyHuddinge University HospitalStockholmSweden
  4. 4.Division of VirologyNational Institute for Biological Standards and ControlPotters BarU.K.
  5. 5.Virus DivisionSaitama Institute of Public HealthSaitamaJapan
  6. 6.Laboratory of Viral Infection, Kitasato Institute for Life SciencesTokyoJapan
  7. 7.Department of MicrobiologyInstitute for Viral Diseases, College of Medicine, Korea UniversitySeoulSouth Korea
  8. 8.Laboratory of Respiratory Viruses, National Institute of HealthSeoulSouth Korea
  9. 9.Measles Section, Centers for Disease Control and PreventionAtlantaU.S.A.
  10. 10.National Laboratory for Measles, Institute of Virology Disease Control and Prevention, Chinese Center for Disease Control and PreventionBeijingChina
  11. 11.Department of ImmunisationVaccines and Biologicals, World Health OrganizationGenevaSwitzerland

Personalised recommendations