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Journal of Neural Transmission

, Volume 126, Issue 12, pp 1609–1616 | Cite as

Physical activity participation according to the pyramidal, sensory, and cerebellar functional systems in multiple sclerosis

  • Alon KalronEmail author
  • Lior Frid
  • Roy Aloni
  • Shay Menascu
  • Uri Givon
Neurology and Preclinical Neurological Studies - Original Article

Abstract

The objective of the study was to examine the differences in physical activity participation with the pyramidal, cerebellar, and sensory functional systems in people with multiple sclerosis (PwMS). This cross-sectional study included 289 PwMS with a median EDSS of 2.0 (range 0–6.5) and a mean disease duration of 6.8 (SD = 8.4) years. The Godin leisure-time exercise questionnaire (GLTEQ) assessed physical activity participation. The sample was divided into seven groups according to the pyramidal, cerebellar, and sensory functional system scores derived from the EDSS data. Additionally, PwMS were divided into three physical activity subgroups (active, moderately active, and insufficiently active). Furthermore, PwMS were categorized into four levels of disability based on their global Expanded Disability Status Scale (EDSS) score [very mild (0–1.5), mild (2.0–3.5), moderate (4.0–5.5), and severe (6.0–6.5)]. In the physical activity subgroups, 159 (55.0%) were classified as insufficiently active, 59 (20.4%) as moderately active, and 71 (24.6%) as active. Pyramidal, cerebellar, and sensory impairments were demonstrated in 134 (46.4%), 73 (25.3%), and 85 (29.4%) patients, respectively. No differences were found for the GLTEQ scores for all seven functional system groups (P value = 0.168). As for the EDSS disability subgroups, the percentage of active patients (moderately at least) were 60%, 45.8%, 36.5%, and 15.4%, for the very mild, mild, moderate, and severe subgroups, respectively. This study found that participation in leisure-time physical activity is independent from the pyramidal, cerebellar, and sensory functional systems in PwMS.

Keywords

Multiple sclerosis Physical activity Pyramidal Sensory Cerebellar 

Notes

Funding

None.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  • Alon Kalron
    • 1
    • 2
    Email author
  • Lior Frid
    • 3
  • Roy Aloni
    • 3
  • Shay Menascu
    • 3
  • Uri Givon
    • 3
  1. 1.Department of Physical Therapy, School of Health Professions, Sackler Faculty of MedicineTel-Aviv UniversityTel-AvivIsrael
  2. 2.Sagol School of NeuroscienceTel-Aviv UniversityTel-AvivIsrael
  3. 3.Multiple Sclerosis Center, Sheba Medical CenterRamat GanIsrael

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