Journal of Neural Transmission

, Volume 121, Issue 2, pp 123–134 | Cite as

The prevalence and incidence of Parkinson’s disease in China: a systematic review and meta-analysis

  • Chun-lin Ma
  • Li Su
  • Juan-juan Xie
  • Jian-xiong Long
  • Peng Wu
  • Lian Gu
Neurology and Preclinical Neurological Studies - Review Article

Abstract

Parkinson’s disease (PD) is a chronic neurodegenerative disorder affecting older individuals. There is inconsistent evidence about the prevalence and incidence of PD in China at present. The aim of the meta-analysis was to estimate the prevalence and incidence of PD and its relation to age, gender, and stage in China. The literature search was conducted using PubMed, EMBASE, Chinese Biological Medical Literature database (CBM), Chinese National Knowledge Infrastructure database (CNKI), Chinese Wanfang and Chongqing VIP database for studies investigating the prevalence and incidence of PD in China from the commencement of the database until August 2012; both English and Chinese publications were included. We estimated the prevalence and incidence of PD using meta-analysis. Thirteen eligible articles were collected. The results showed that the pooled prevalence and incidence of PD were 2 per 100,000 population and 797 per 100,000 person-years. A higher prevalence of PD was found in males than in females (OR 1.29, 95 % CI 1.05–1.57). The prevalence of PD increased with age: the highest was 1,663 per 100,000 in those aged 80 and older. The overall prevalence of PD is lower in China than in developed countries, but the incidence is higher than in some developed countries. Overall, the prevalence of PD appears to increase with age and there are sex differences evident in Chinese individuals.

Keywords

Parkinson’s disease Prevalence Incidence Review Meta-analysis 

Supplementary material

702_2013_1092_MOESM1_ESM.doc (38 kb)
Supplementary material 1 (DOC 38 kb)
702_2013_1092_MOESM2_ESM.doc (20 kb)
Supplementary material 2 (DOC 19 kb)

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Copyright information

© Springer-Verlag Wien 2013

Authors and Affiliations

  • Chun-lin Ma
    • 1
  • Li Su
    • 2
  • Juan-juan Xie
    • 3
  • Jian-xiong Long
    • 2
  • Peng Wu
    • 3
  • Lian Gu
    • 3
  1. 1.Department of Intensive Care Unit, First Affiliated Hospital, Guangxi University of Chinese MedicineNanningChina
  2. 2.School of Public Health of Guangxi Medical UniversityNanningChina
  3. 3.Department of Internal Neurology, First Affiliated Hospital, Guangxi University of Chinese MedicineNanningChina

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