Journal of Neural Transmission

, Volume 120, Issue 10, pp 1441–1445

A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection

  • Phanichand Kodali
  • Julio A. Landero-Figueroa
  • Joseph Caruso
  • Opeolu Adeoye
Neurology and Preclinical Neurological Studies - Short communication


Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.


Blood plasma Biomarkers HPLC Stroke 


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Copyright information

© Springer-Verlag Wien 2013

Authors and Affiliations

  • Phanichand Kodali
    • 1
  • Julio A. Landero-Figueroa
    • 1
  • Joseph Caruso
    • 1
  • Opeolu Adeoye
    • 2
  1. 1.Department of ChemistryUniversity of CincinnatiCincinnatiUSA
  2. 2.Department of Emergency MedicineUniversity of CincinnatiCincinnatiUSA

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