Inflammation processes in perinatal brain damage
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Once viewed as an isolated, immune-privileged organ, the central nervous system has undergone a conceptual change. Neuroinflammation has moved into the focus of research work regarding pathomechanisms underlying perinatal brain damage. In this review, we provide an overview of current concepts regarding perinatal brain damage and the role of inflammation in the disease pathomechanism.
KeywordsNeuroinflammation Perinatal brain damage Microglia Cytokines
Our research work is supported by Inserm, Université Paris 7, PremUP, the Sixth Framework Program of the European Commission, the Fondation des Gueules Cassées, the Fondation Motrice, the ELA Foundation, the Fondation Grace de Monaco, the Institut pour la Recherche sur la Moelle épinière et l’Encéphale (IRME), the Medical Research Council, the Charité, the German Research Foundation (DFG), the German Federal Ministry of Education and Research, the Sonnenfeld Stiftung and the Sanitätsrat Dr.-Emil-Alexander-Huebner-und-Gemahlin-Stiftung.
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