Unexpected immediate postoperative resolution of long-standing neurological deficits following extracranial-intracranial bypass: a report of three cases
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While intracranial ischemic insults often result in neuronal death and permanent neurological deficits, some patients may develop potentially reversible neurological dysfunction from persistent hypoperfusion, as surviving neurons remain in an “idling” state. We report a unique series of three patients with long-standing neurological deficits who underwent EC-IC bypass for repeated TIAs and demonstrated unexpected, rapid resolution of long-standing pre-existing neurological deficits. We suggest that these individuals harbored regions of underperfused, idling neurons that responded rapidly to restored cerebral reperfusion.
KeywordsExtracranial-intracranial bypass Leg plegia Perfusion
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We received a grant from the United Hospital Foundation to support this work.
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Conflict of interest
Kevin Kallmes works for and holds equity in Superior Medical Experts. The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.
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