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Acta Neurochirurgica

, Volume 160, Issue 4, pp 783–792 | Cite as

Successful microsurgical treatment of intracranial aneurysms in infants: a retrospective study and literature review

  • Yanming Ren
  • Shuzhen Zhao
  • Lunxin Liu
  • Hong Sun
  • Yi Liu
  • Hao Li
  • Lu Ma
  • Min He
  • Chao YouEmail author
  • Jin LiEmail author
Original Article - Pediatrics

Abstract

Objective

Intracranial aneurysms are extremely rare in infants, especially less than 1 year old. This study aimed to analyze the frequency of infantile intracranial aneurysm in our department and investigate the clinical characteristics, treatment strategies, and outcomes of this disease.

Methods

Six infants under 1 year old in 4350 patients with intracranial aneurysms were retrospectively analyzed from January 2010 to December 2016.

Results

The patients (5 females and 1 male) ranged in age from 2 to 11 (mean age, 4.67) months. Four patients presented with generalized seizure and vomiting, 3 showed lethargy, 1 presented eye deviation, and 1 had right-sided hemiparesis. Radiographically, two aneurysms were localized in the middle cerebral artery (MCA) of the M2 segment, two were located in the M3 segment of MCA, one was located at left MCA bifurcation, and one was located at the nonbranching site of the left supraclinoid internal carotid artery. All these lesions were successfully managed with aneurysm clipping or resection, and the improvement of neurological deficits was achieved in all patients.

Conclusion

Intracranial aneurysms should be considered in the differential diagnosis of infants who present with acute raised intracranial pressure. An improvement of neurological deficits is noted in infants who are managed promptly with microsurgical techniques of clipping during the long-term follow-up.

Keywords

Infantile intracranial aneurysm Aneurysm Microsurgery 

Abbreviations

CT

computed tomography

CTA

computed tomography angiography

DSA

digital subtraction angiography

IPH

intraparenchymal hemorrhage

MCA

middle cerebral artery

SAH

subarachnoid hemorrhage

PICH

pediatric intense care unit

ICG

indocyanine green

PICA

posterior inferior cerebellar artery

IVH

intraventricular hemorrhage

Notes

Acknowledgements

None.

Funding

This work was supported by Science and technology supportive project of Sichuan Province (2015SZ0051) and Natural Science Foundation of China (81571131).

Compliance with ethical standards

Compliance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Yanming Ren
    • 1
  • Shuzhen Zhao
    • 2
  • Lunxin Liu
    • 1
  • Hong Sun
    • 1
  • Yi Liu
    • 1
  • Hao Li
    • 1
  • Lu Ma
    • 1
  • Min He
    • 1
  • Chao You
    • 1
    Email author
  • Jin Li
    • 1
    Email author
  1. 1.Department of NeurosurgeryWest China Hospital, Sichuan UniversityChengduChina
  2. 2.Department of Nurse, West China HospitalSichuan UniversityChengduChina

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