Acta Neurochirurgica

, Volume 160, Issue 4, pp 801–809 | Cite as

Parapharyngeal neuroglial heterotopia appearing as high uptake on 18F–FDG PET: case report and literature review of radiographical findings

  • Masayuki Kameyama
  • Tomohiro Kawaguchi
  • Hidetaka Niizuma
  • Takenori Ogawa
  • Kenichi Watanabe
  • Toshiaki Hayashi
  • Kanako Sato
  • Masayuki Kanamori
  • Mika Watanabe
  • Yukio Katori
  • Shigeo Kure
  • Teiji Tominaga
Case Report - Pediatrics


Parapharyngeal neuroglial heterotopia is a rare entity, and the specific radiographical findings are unclear. We present a case of parapharyngeal neuroglial heterotopia examined with proton magnetic resonance spectroscopy (1H–MRS) and 18F–fluorodesoxyglucose positron emission tomography (18F–FDG PET). Our neonate patient presented with neck mass and polyhydramnios during gestation. Computed tomography and magnetic resonance imaging demonstrated the morphological characteristics, but failed to establish the diagnosis. 1H–MRS showed a non-malignant pattern, but 18F–FDG PET demonstrated high glucose metabolism. Complete resection was achieved and the histopathological diagnosis was neuroglial heterotopia. Assessment of biological activity may be useful for both preoperative diagnosis and postoperative evaluation of residual lesions.


Neuroglial heterotopia 18F–FDG pet 1H–MRS Differential diagnosis 


Compliance with ethical standards

Conflict of interest


Informed consent

The patient’s kin has consented to submission of this case report to the journal.


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2017

Authors and Affiliations

  • Masayuki Kameyama
    • 1
  • Tomohiro Kawaguchi
    • 1
  • Hidetaka Niizuma
    • 2
  • Takenori Ogawa
    • 3
  • Kenichi Watanabe
    • 3
  • Toshiaki Hayashi
    • 1
  • Kanako Sato
    • 1
  • Masayuki Kanamori
    • 1
  • Mika Watanabe
    • 4
  • Yukio Katori
    • 3
  • Shigeo Kure
    • 2
  • Teiji Tominaga
    • 1
  1. 1.Department of NeurosurgeryTohoku University Graduate School of MedicineSendaiJapan
  2. 2.Department of PediatricsTohoku University Graduate School of MedicineSendaiJapan
  3. 3.Department of Otolaryngology-Head and Neck SurgeryTohoku University Graduate School of MedicineSendaiJapan
  4. 4.Department of PathologyTohoku University Graduate School of MedicineSendaiJapan

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