Acta Neurochirurgica

, Volume 159, Issue 8, pp 1511–1515 | Cite as

5-ALA fluorescence in intraparenchymal endodermal cysts

  • José Pedro Lavrador
  • Christian Brogna
  • Francesco Vergani
  • Fay Greenway
  • Miren Aizpurua
  • Ranj Bhangoo
Case Report - Neurosurgical Techniques


In recent years, new indications have been suggested for 5-ALA, particularly for cystic lesions. We report the use of 5-ALA fluorescence in an intraparenchymal supratentorial endodermal cyst of a 52-year-old female presenting with headache, progressive right side hemiparesis and anomic aphasia. She underwent an image-guided 5-ALA-assisted left minicraniotomy for fenestration of the cystic lesion into the ventricular system. The capsule of the cyst was noted to fluoresce with 5-ALA. She recovered from the previous deficits and the cyst decreased in size. To the best of our knowledge, this is the first time 5-ALA fluorescence is reported in a case of endodermal cyst.


5-ALA Endodermal cyst Tumour This work has not been presented in a conference. 


Compliance with ethical standards


No funding was received for this research.

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licencing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Patient consent

The patient has consented to submission of this case report to the journal.


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Copyright information

© Springer-Verlag Wien 2017

Authors and Affiliations

  • José Pedro Lavrador
    • 1
  • Christian Brogna
    • 1
    • 2
  • Francesco Vergani
    • 1
  • Fay Greenway
    • 1
  • Miren Aizpurua
    • 3
  • Ranj Bhangoo
    • 1
  1. 1.Department of NeurosurgeryKing’s College Hospital NHS Foundation TrustLondonUK
  2. 2.Maurice Wohl Clinical Neuroscience InstituteKing’s College LondonLondonUK
  3. 3.Department of NeuropathologyKing’s College Hospital NHS Foundation TrustLondonUK

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