Bilateral pallidotomy for Meige syndrome

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Meige syndrome (MS) is usually described as a combination of blepharospasm with oromandibular dystonia. There are a large number of case reports of deep brain stimulation (DBS) of the globus pallidus internus (GPI) for MS and only one report of unilateral pallidotomy (PT). We report the first case of staged bilateral PT for treatment of a patient with MS using intraoperative high-frequency stimulation in order to predict and prevent postoperative deficit. There was a significant improvement of the Burk-Fahn-Marsden dystonia rating scale from 26 to 3. There were no adverse postoperative neurological and neuropsychological events.

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Author information

Correspondence to Krasimir Minkin.

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Additional information


In this era of DBS hysteria, there are people who still believe in the benefit of non-expensive and well-performed stereotactic lesional procedures, and provide solid documentation about its benefit. This paper is one of them.

Marwan Hariz

London, UK

Electronic supplementary material

Preoperative video (MOV 43595 kb)

Postoperative video 3 days after left-sided PT (MOV 45170 kb)

Postoperative video 24 months after bilateral PT (MOV 43205 kb)

Preoperative video (MOV 43595 kb)

Postoperative video 3 days after left-sided PT (MOV 45170 kb)

Postoperative video 24 months after bilateral PT (MOV 43205 kb)

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Minkin, K., Gabrovski, K., Dimova, P. et al. Bilateral pallidotomy for Meige syndrome. Acta Neurochir 159, 1359–1363 (2017).

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  • Dystonia
  • Meige syndrome
  • Deep brain stimulation
  • Pallidotomy
  • Radiofrequency lesions
  • High frequency stimulation