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Acta Neurochirurgica

, Volume 156, Issue 7, pp 1335–1339 | Cite as

Age delays the recovery of distal motor latency after carpal tunnel syndrome surgery

  • O. Vyšata
  • A. Procházka
  • P. Kunc
  • M. Kanta
  • E. Ehler
  • M. Yadollahi
  • M. VališEmail author
Clinical Article - Neurosurgical Techniques

Abstract

Background

Studies have shown slow healing of peripheral nerve injury in elderly patients. Carpal tunnel syndrome (CTS) is the most frequent compressive mononeuropathy, affecting mostly older people and females. Few studies have assessed electrophysiological differences between younger and older patients. We aimed to evaluate age-dependent differences in electrophysiological parameters preoperatively and postoperatively over a 100-day postoperative period.

Method

This retrospective study included 258 hands of patients who underwent conventional open-technique carpal tunnel syndrome surgery. Patients with paresthesia in the median nerve distribution or with impaired sensation or abnormal findings in sensory and motor median nerve conduction studies were enrolled. The age dependence of the preoperative values of distal motor latency, amplitude of the compound motor action potential and sensory conduction velocity was estimated using regression analysis.

Results

Statistically significant age dependence was found for the preoperative distal motor latency, compound motor action potential, amplitude and sensory conduction velocity. The repair of segmental demyelination was nearly twice as slow in the older group, at a 5 % significance level, even when comparing groups with the same preoperative distal motor latency.

Conclusions

Analysis of preoperative nerve conduction parameters indicates that surgery for carpal tunnel syndrome is performed later in older patients.

Keywords

Carpal tunnel syndrome Median nerve Nerve conduction studies Open carpal tunnel release Age-dependent recovery Distal motor latency 

Notes

Acknowledgments

Supported by MH CZ-DRO (UHHK, 00179906).

Conflicts of interest

None.

References

  1. 1.
    Assmus H, Antoniadis G, Bischoff C, Haussmann P, Martini AK, Mascharka Z, Scheglmann K, Schwerdtfeger K, Selbmann HK, Towfigh H, Vogt T, Wessels KD, Wüstner-Hofmann M (2007) [Diagnosis and therapy of carpal tunnel syndrome—guideline of the German Societies of Handsurgery, Neurosurgery, Neurology, Orthopaedics, Clinical Neurophysiology and Functional Imaging, Plastic, Reconstructive and Aesthetic Surgery, and Surgery for Traumatology]. Handchir Mikrochir Plast Chir 39:276–288PubMedCrossRefGoogle Scholar
  2. 2.
    Becker J, Scalco RS, Pietroski F, Celli LF, Gomes I (2013) Is carpal tunnel syndrome a slow, chronic, progressive nerve entrapment? Clin Neurophysiol 8:S1388–S2001Google Scholar
  3. 3.
    Kanta M, Ehler E, Kremlácek J, Rehák S, Lastovicka D, Adamkov J, Habalová J, Bartos M (2009) The potential benefit of intracarpal pressure measurement in endoscopic carpal tunnel syndrome surgery—an analysis of EMG findings and pressure values. Acta Medica (Hradec Kralove) 52:63–68Google Scholar
  4. 4.
    Katz JN, Losina E, Amick BC 3rd, Fossel AH, Bessette L, Keller RB (2001) Predictors of outcomes of carpal tunnel release. Arthritis Rheum 44:1184–1193PubMedCrossRefGoogle Scholar
  5. 5.
    Shifflett GD, Dy CJ, Daluiski A (2012) Carpal tunnel surgery: patient preferences and predictors for satisfaction. Patient Prefer Adherence 6:685–689PubMedCentralPubMedGoogle Scholar
  6. 6.
    Schlagenhauff RE, Glasauer FE (1971) Pre- and postoperative electromyographic evaluations in the carpal tunnel syndrome. J Neurosurg 35:314–319PubMedCrossRefGoogle Scholar
  7. 7.
    Turner A, Kimble F, Gulyás K, Ball J (2010) Can the outcome of open carpal tunnel release be predicted?: a review of the literature. ANZ J Surg 80:50–54PubMedCrossRefGoogle Scholar
  8. 8.
    Vaughan DW (1992) Effects of advancing age on peripheral nerve regeneration. J Comp Neurol 323:219–237PubMedCrossRefGoogle Scholar
  9. 9.
    Verdú E, Ceballos D, Vilches JJ, Navarro X (2005) Influence of aging on peripheral nerve function and regeneration. J Peripher Nerv Syst 5:191–208CrossRefGoogle Scholar
  10. 10.
    Weber RA, DeSalvo DJ, Rude MJ (2010) Five-year follow-up of carpal tunnel release in patients over age 65. J Hand Surg Am 35:207–211PubMedCrossRefGoogle Scholar
  11. 11.
    Xu QG, Midha R, Martinez JA, Guo GF, Zochodne DW (2008) Facilitated sprouting in a peripheral nerve injury. Neuroscience 152:877–887PubMedCrossRefGoogle Scholar
  12. 12.
    Zyluk A, Puchalski P (2013) A comparison of the results of carpal tunnel release in patients in different age groups. Neurol Neurochir Pol 47:241–246PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Wien 2014

Authors and Affiliations

  • O. Vyšata
    • 1
    • 2
  • A. Procházka
    • 1
  • P. Kunc
    • 2
  • M. Kanta
    • 4
  • E. Ehler
    • 3
  • M. Yadollahi
    • 1
  • M. Vališ
    • 2
    Email author
  1. 1.Department of Computing and Control EngineeringInstitute of Chemical TechnologyPrague 6Czech Republic
  2. 2.Department of NeurologyUniversity Hospital Hradec Králové, Charles University in Prague, Faculty of Medicine in Hradec KrálovéHradec KrálovéCzech Republic
  3. 3.Department of NeurologyRegional Hospital in Pardubice, Faculty of Health-Care, University of PardubicePardubiceCzech Republic
  4. 4.Department of NeurosurgeryUniversity Hospital Hradec Králové, Charles University in Prague, Faculty of Medicine in Hradec KrálovéHradec KrálovéeCzech Republic

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