Brissaud-Sicard syndrome caused by a diffuse brainstem glioma. A rare differential diagnosis of hemifacial spasm
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Brissaud-Sicard syndrome is a pontine-crossed syndrome, which obligatorily comprises ipsilateral facial cramps and contralateral hemiparesis. The syndrome was first described by the French physician Adolphe Gubler in 1856 . However, the syndrome bears the name of two other French physicians, Edouard Brissaud and Jean Athanase Sicard. In 1908, they provided a very detailed clinical description of three patients, who were claimed to suffer from syphilis with secondary cerebro-vascular involvement. The authors argued that there was a lesion in the pyramidal tract in the basilar pons with additional irritation of the intrapontine fibres of the facial nerve. No post-mortem examination was performed in these cases .
The constellation of the obligatory symptoms is very rare and has been reported only twice in patients suffering from pontine strokes since the original publication .
Hemifacial spasm is a common movement disorder that is caused by the mechanical irritation...
KeywordsFacial Nerve Facial Muscle Hemifacial Spasm Brainstem Glioma French Physician
Conflicts of interest
- 1.Brissaud E, Sicard J (1908) A L’hémispasme facial alterne. Le Presse médicale 16:234–236Google Scholar
- 2.Gubler A (1856) De l’Hémiplégie alterneen visage comme signe et lésion de la protuberance annulaire et comme preuve de la décussation des nerfs faciaux. Gazette hebdomadaire de medicine et de chirurgie 3:749–816, 789–792, 811–816Google Scholar