Acta Neurochirurgica

, Volume 154, Issue 2, pp 369–370 | Cite as

Angiosarcoma of the liver with metastasis to the cervical spine cured with the treatment of thalidomide and radiotherapy

  • Selim KayaciEmail author
  • Ozcan Yildiz
  • Hasan Gucer
  • Nil Molinas Mandel
Letter to the Editor

Dear Editor,

We would like to present a unique case of metastatic angiosarcoma of the cervical spine treated with thalidomide.

A 62-year-old male patient presented at the general surgery outpatient clinic with pain in his back and epigastric area, which had lasted for several days. On examination, epigastric tenderness was noted and the liver was palpable. There were extralobular growths adjacent to the vascular structures on the abdominal magnetic resonance imaging (MRI). A biopsy was taken from the masses that largely occupied the left lobe of the liver. Histopathological examination revealed infiltration of the hepatic tissue with epitheloid-like cells that had large vesicular nuclei and eosinophilic cytoplasms, and with proliferating tumour cells with mitotic activity. Angiosarcoma was diagnosed according to above pathological findings. The patient declined a second operation, which was recommended for the removal of the remaining part of the tumour.

It was decided to treat the...


Cervical Spine Thalidomide Hemangioma Angiosarcoma Abdominal Magnetic Resonance Imaging 
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Conflicts of interest



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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Selim Kayaci
    • 1
    Email author
  • Ozcan Yildiz
    • 2
  • Hasan Gucer
    • 3
  • Nil Molinas Mandel
    • 2
  1. 1.Department of Neurosurgery, School of MedicineRize UniversityRizeTurkey
  2. 2.Department of Oncology, Cerrahpasa School of MedicineIstanbul UniversityIstanbulTurkey
  3. 3.Department of Pathology, School of MedicineRize UniversityRizeTurkey

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