Angiosarcoma of the liver with metastasis to the cervical spine cured with the treatment of thalidomide and radiotherapy
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We would like to present a unique case of metastatic angiosarcoma of the cervical spine treated with thalidomide.
A 62-year-old male patient presented at the general surgery outpatient clinic with pain in his back and epigastric area, which had lasted for several days. On examination, epigastric tenderness was noted and the liver was palpable. There were extralobular growths adjacent to the vascular structures on the abdominal magnetic resonance imaging (MRI). A biopsy was taken from the masses that largely occupied the left lobe of the liver. Histopathological examination revealed infiltration of the hepatic tissue with epitheloid-like cells that had large vesicular nuclei and eosinophilic cytoplasms, and with proliferating tumour cells with mitotic activity. Angiosarcoma was diagnosed according to above pathological findings. The patient declined a second operation, which was recommended for the removal of the remaining part of the tumour.
KeywordsCervical Spine Thalidomide Hemangioma Angiosarcoma Abdominal Magnetic Resonance Imaging
Conflicts of interest
- 5.Sasaki R, Soejima T, Kishi K, Imajo Y, Hirota S, Kamikonya N, Murakami M, Kawabe T, Ejima Y, Matsumoto A, Sugimura K (2002) Angiosarcoma treated with radiotherapy: impact of tumor type and size on outcome. Int J Radiat Oncol Biol Phys 15:1032–1040Google Scholar