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Acta Neurochirurgica

, Volume 152, Issue 12, pp 2029–2036 | Cite as

Is MRI a reliable tool to locate the electrode after deep brain stimulation surgery? Comparison study of CT and MRI for the localization of electrodes after DBS

  • Ji Yeoun Lee
  • Jin Wook Kim
  • Jee-Young Lee
  • Yong Hoon Lim
  • Cheolyoung Kim
  • Dong Gyu Kim
  • Beom Seok JeonEmail author
  • Sun Ha PaekEmail author
Clinical Article

Abstract

Purpose

MRI has been utilized to localize the electrode after deep brain stimulation, but its accuracy has been questioned due to image distortion. Under the hypothesis that MRI is not adequate for evaluation of electrode position after deep brain stimulation, this study is aimed at validating the accuracy of MRI in electrode localization in comparison with CT scan.

Methods

Sixty one patients who had undergone STN DBS were enrolled for the analysis. Using mutual information technique, CT and MRI taken at 6 months after the operation were fused. The x and y coordinates of the centers of electrodes shown of CT and MRI were compared in the fused images to calculate average difference at five different levels. The difference of the tips of the electrodes, designated as the z coordinate, was also calculated.

Results

The average of the distance between the centers of the electrodes in the five levels estimated in the fused image of brain CT and MRI taken at least 6 months after STN DBS was 1.33 mm (0.1–5.8 mm). The average discrepancy of x coordinates for all five levels between MRI and CT was 0.56 ± 0.54 mm (0–5.7 mm), the discrepancy of y coordinates was 1.06 ± 0.59 mm (0–3.5 mm), and for the z coordinate, it was 0.98 ± 0.52 mm (0–3.1 mm) (all p values < 0.001). Notably, the average discrepancy of x coordinates at 3.5 mm below AC–PC level, i.e., at the STN level between MRI and CT, was 0.59 ± 0.42 mm (0–2.4 mm); the discrepancy of y coordinates was 0.81 ± 0.47 mm (0–2.9 mm) (p values < 0.001).

Conclusions

The results suggest that there was significant discrepancy between the centers of electrodes estimated by CT and MRI after STN DBS surgery.

Keywords

CT DBS Electrode localization Image fusion MRI Parkinson's disease 

Notes

Acknowledgements

This study was supported by a grant of the Korea Healthcare technology R&D Project, Ministry for Health, Welfare & Family Affairs, Republic of Korea (A092052).

Conflicts of interest

None.

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Ji Yeoun Lee
    • 1
  • Jin Wook Kim
    • 1
  • Jee-Young Lee
    • 2
  • Yong Hoon Lim
    • 1
  • Cheolyoung Kim
    • 6
  • Dong Gyu Kim
    • 1
  • Beom Seok Jeon
    • 2
    • 5
    Email author
  • Sun Ha Paek
    • 1
    • 3
    • 4
    • 5
    Email author
  1. 1.Department of NeurosurgerySeoul National University College of MedicineSeoulSouth Korea
  2. 2.Department of NeurologySeoul National University College of MedicineSeoulSouth Korea
  3. 3.Ischemic/Hypoxic Disease InstituteSeoul National University College of MedicineSeoulSouth Korea
  4. 4.Cancer Research InstituteSeoul National University College of MedicineSeoulSouth Korea
  5. 5.Clinical Research InstituteSeoul National University HospitalSeoulSouth Korea
  6. 6.Medical Imaging LaboratoryCyberMed, Inc.SeoulSouth Korea

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