Acta Neurochirurgica

, 151:415 | Cite as

Hyperbaric oxygen in neurosurgery

  • B. R. Fischer
  • E. J. Speckmann
  • C. Greiner
  • A. Gorji
  • J. Wölfer
  • H. WassmannEmail author
Historical Note



The therapeutic use of pure oxygen, even under hyperbaric conditions, has been well established for about 50 years, whereas the discovery of oxygen occurred 250 years earlier. Many neurosurgical patients suffer from brain tissue damage, due to reduced blood flow, obstructive vessel disease, or as a result of traumatic brain injury.

Methods and results

The application of pure oxygen in these patients is the only method of increasing the O2 concentration in tissue with impaired blood supply and can minimize secondary impairment of brain tissue.


In this brief historical overview we focus on the development and evidence of hyperbaric oxygenation in this specific field of insufficient oxygen supply to the central neural tissue.


With the use of modern biological methods and new study designs, HBO has a place in evidence-based treatment of patients with neural tissue damage.


Hyperbaric oxygenation Stroke Traumatic brain injury History 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • B. R. Fischer
    • 1
  • E. J. Speckmann
    • 2
  • C. Greiner
    • 1
  • A. Gorji
    • 2
  • J. Wölfer
    • 1
  • H. Wassmann
    • 1
    Email author
  1. 1.Department of NeurosurgeryUniversity Hospital of Münster (UKM)MünsterGermany
  2. 2.Institute for Physiology IUniversity Hospital MünsterMünsterGermany

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